Results 61 to 70 of about 813,266 (291)
Advancing Exoskeleton Development: Validation of a Robotic Surrogate to Measure Tibial Strain
BioengineeringBone stress injuries are prevalent among athletes and military recruits and can significantly compromise training schedules. The development of an ankle–foot orthosis to reduce tibial load and enable a faster return to activity will require new device ...
Robert L. McGrath +3 more
doaj +1 more source
Biomechanical Modeling of Human Skin Tissue Surrogates
Biomimetics, 2018 Surrogates, which precisely simulate nonlinear mechanical properties of the human skin at different body sites, would be indispensable for biomechanical testing applications, such as estimating the accurate load response of skin implants and prosthetics ...
Arnab Chanda
doaj +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
End-to-end optimal detector design with mutual information surrogates
Machine Learning: Science and TechnologyWe introduce a novel approach for end-to-end black-box optimization of high energy physics (HEP) detectors using local deep learning surrogates. These surrogates approximate a scalar objective function that encapsulates the complex interplay of particle ...
Kinga Anna Woźniak +5 more
doaj +1 more source
Limitations of polynomial chaos expansions in the Bayesian solution of inverse problems
, 2014 Polynomial chaos expansions are used to reduce the computational cost in the Bayesian solutions of inverse problems by creating a surrogate posterior that can be evaluated inexpensively.
Chorin, Alexandre J. +3 more
core +1 more source
Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Creating a Real‐Time Capable Surrogate Model of a Wind Turbine Using Machine Learning
Wind EnergyMultibody simulation (MBS) is an established method for modeling wind turbines for purposes such as load calculation. While capable of modeling wind turbines at high levels of detail, large MBS models can be computationally expensive.
Stefan Witter +3 more
doaj +1 more source
International Journal of COPD, 2020 Balazs Antus,1,2 Csilla Paska,1 Imre Barta1 1Department of Pathophysiology, National Koranyi Institute of Pulmonology, Budapest H-1121, Hungary; 2Department of Pulmonology, National Koranyi Institute of Pulmonology, Budapest H-1121, HungaryCorrespondence:
Antus B, Paska C, Barta I
doaj
Inference in Complex Systems Using Multi-Phase MCMC Sampling With Gradient Matching Burn-in [PDF]
, 2017 We propose a novel method for parameter inference that builds on the current research in gradient matching surrogate likelihood spaces. Adopting a three phase technique, we demonstrate that it is possible to obtain parameter estimates of limited bias ...
Husmeier, Dirk +2 more
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