Results 181 to 190 of about 578,456 (312)

Proteomic blood-based biomarkers of brain damage in traumatic brain injury: are they suitable surrogate endpoints for cerebral pressure autoregulatory-guided therapy? [PDF]

Crit Care
Kevci R, Hånell A, Aries M, Åkerlund C, Buki A, Bhattacharyay S, Di Tommaso G, Hendrix R, Newcombe V, Lewén A, Enblad P, Beqiri E, Smielewski P, Wettervik TS, HR subgroup CENTER-TBI collaborators.   +14 more
europepmc   +1 more source

Surrogate Endpoints for Overall Survival in Cancer Randomized Controlled Trials

, 2017
Dans les essais cliniques randomisés (ECR) en cancérologie, un critère de substitution est une mesure biologique utilisée à la place d’un critère cliniquement pertinent pour le patient, par exemple la survie globale (SG), qui doit permettre de prédire l ...
Savina, Marion
core  

Fatigue Crack Initiation and Growth in Nanocrystalline Ni at Multiple Length‐Scales

Advanced Engineering Materials, EarlyView.
Overview of miniaturized in situ SEM fatigue setup and resultant fatigue crack growth data for nanocrystalline Ni. The presented study focuses on the analysis of fatigue crack growth rate (FCGR) in focused ion beam‐notched microcantilevers prepared from nanocrystalline (NC) Ni as a model material.
Igor Moravcik, Alexander Jelinek, Markus Alfreider, Jutta Luksch, Anton Hohenwarter, Florian Schaefer, Christian Motz, Daniel Kiener   +7 more
wiley   +1 more source

Enhancing reporting and interpretation of surrogate endpoints in rehabilitation randomized controlled trials: a scoping review

Purpose: This study aimed to identify and audit rehabilitation randomized controlled trials (RCTs) that used surrogate endpoints, evaluating the completeness and transparency of reporting based on the recently developed SPIRIT- (Standard Protocol Items:
Faria, Christina D.C.M., Scianni, Aline Alvim, Polese, Janaine Cunha, Taylor, Rod S., Ciani, Oriana, Manyara, Anthony Muchai   +5 more
core   +1 more source

Bayesian meta-analytical methods to incorporate multiple surrogate endpoints in drug development process. [PDF]

Stat Med, 2022
Bujkiewicz S.
europepmc   +1 more source

Creep Properties and Deformation Mechanism of Additively Manufactured NiAl‐CrMo Composites

Advanced Engineering Materials, EarlyView.
Additively manufactured NiAl‐CrMo composites contain numerous interfaces and cell boundaries that control their creep response. At 700°C under high applied stress, creep is dominated by dislocation‐controlled power‐law mechanisms. At 800°C–900°C and lower stresses, creep is primarily diffusion‐controlled along cell boundaries.
Jan Vollhüter, Andreas Bezold, Johan Westraadt, Katharina Fiegl, Subham Chattoraj, Benjamin Wahlmann, Carolin Körner, Michael Mills, Mathias Göken, Steffen Neumeier   +9 more
wiley   +1 more source

A call for better reporting of trials using surrogate primary endpoints

Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2022
Anthony Muchai Manyara, Oriana Ciani, Rod S. Taylor   +2 more
doaj   +1 more source

Current Status and Challenges in Data Collection for Aerospace Coatings Deposited by Plasma Spraying

Advanced Engineering Materials, EarlyView.
An innovative approach has been integrated into the GRENAT project to optimize plasma spraying and coating performance. Raw materials are accelerated and melted in the plasma generated by torches, creating coatings. Monitoring sensors collect process data which are combined with ex situ characterization data.
Lila Randriamananjara, Vincent Rat, Quentin Dubreuil, Patrice Valorge, Simon Goutier, Alain Denoirjean, Olivier Messe, Céline Ruelle, Jean‐Philippe Poli   +8 more
wiley   +1 more source

Significance of biomarkers and surrogate endpoints in preclinical and clinical trials [PDF]

Vojnosanitetski Pregled, 2007
Ilić Katarina, Kuntić Vesna
doaj   +1 more source

Association Between Surrogate Endpoints and Clinical Outcomes in Immunoglobulin A Nephropathy: A Systematic Literature Review. [PDF]

Adv Ther
Lorenzi M, Ali SN, Cadarette S, Ebohon S, Diaby V, Mathur M, Fernandes AW.   +6 more
europepmc   +1 more source