Results 21 to 30 of about 145,000 (257)

Association Between the Surrogate Markers of Insulin Resistance and Chronic Kidney Disease in Chinese Hypertensive Patients

Frontiers in Medicine, 2022
BackgroundWe aim to evaluate the four surrogate markers of insulin resistance (IR), including triglyceride-glucose index (TyG), lipid accumulation product index (LAP), visceral adiposity index (VAI), triglycerides to high-density lipoprotein cholesterol ...
Yumeng Shi, Yumeng Shi, Lihua Hu, Minghui Li, Wei Zhou, Wei Zhou, Wei Zhou, Tao Wang, Tao Wang, Tao Wang, Lingjuan Zhu, Lingjuan Zhu, Lingjuan Zhu, Huihui Bao, Huihui Bao, Huihui Bao, Xiaoshu Cheng, Xiaoshu Cheng, Xiaoshu Cheng, Ping Li, Ping Li, Ping Li   +21 more
doaj   +1 more source

The usefulness of information on HDL-cholesterol: potential pitfalls of conventional assumptions

Current Controlled Trials in Cardiovascular Medicine, 2001
Treatment decisions related to disease prevention are often based on two conventional and related assumptions. First, an intervention-induced change in a surrogate marker (such as high-density lipoprotein [HDL]-cholesterol) in the desired direction ...
Furberg Curt D
doaj   +1 more source

Evaluation of longitudinal surrogate markers

Biometrics, 2020
AbstractThe use of surrogate markers to examine the effectiveness of a treatment has the potential to decrease study length and identify effective treatments more quickly. Most available methods to investigate the usefulness of a surrogate marker involve restrictive parametric assumptions and tend to focus on settings where the surrogate is measured at
Denis Agniel, Layla Parast
openaire   +4 more sources

Surrogate Sonographic Markers of Atherosclerosis [PDF]

Stroke, 2006
To the Editor: We read with interest the work of Staub and coworkers for the comparison of internal carotid artery resistive index (RI) with the common carotid artery intima-media thickness in the prediction of cardiovascular morbidity and mortality.
Abbas, Mohammed Abdalla, Corea, Francesco   +1 more
openaire   +3 more sources

Surrogate Adiposity Markers and Mortality

JAMA Network Open, 2023
ImportanceBody mass index (BMI) is an easily obtained adiposity surrogate. However, there is variability in body composition and adipose tissue distribution between individuals with the same BMI, and there is controversy regarding the BMI associated with the lowest mortality risk.ObjectiveTo evaluate which of BMI, fat mass index (FMI), and waist-to-hip
Khan, Irfan, Le, Ann, Brinza, Christina, Chong, Michael, Mohammadi-Shemirani, Pedrum, Morton, Robert, Kiflen, Michel, Narula, Sukrit, Akhabir, Loubna, Mao, Shihong, Morrison, Katherine, Pigeyre, Marie, Pare, Guillaume   +12 more
openaire   +3 more sources

Surrogate Markers of Antiangiogenic Therapies [PDF]

, 2010
The development of antiangiogenic compounds for the treatment of cancer has indicated a need for new clinical tools to evaluate their efficacy, to assess the optimal dose with minimal side-effects and to early select patients who might benefit from antiangiogenic therapies.
Boven, Epie, Meijerink, Martijn R., Vroling, Laura, Van Der Veldt, Astrid A.M.   +3 more
openaire   +5 more sources

Evaluation of Disease Activity in Inflammatory Bowel Disease: Diagnostic Tools in the Assessment of Histological Healing

Biomedicines, 2023
Inflammatory bowel disease (IBD) comprises two types of chronic intestinal disorders: Crohn’s disease and ulcerative colitis. In long-standing ulcerative colitis disease activity, histological persistent inflammation has been linked to an increased risk ...
Alina Ecaterina Jucan, Otilia Gavrilescu, Mihaela Dranga, Iolanda Valentina Popa, Ioana-Ruxandra Mihai, Vasile-Claudiu Mihai, Gabriela Stefanescu, Vasile Liviu Drug, Cristina Cijevschi Prelipcean, Radu-Alexandru Vulpoi, Oana-Bogdana Barboi, Irina Ciortescu, Catalina Mihai   +12 more
doaj   +1 more source

Association between Immune Markers and Surrogate Markers of Cardiovascular Disease in HIV Positive Patients: A Systematic Review.

PLoS ONE, 2017
BackgroundHIV infection is associated with an increased risk of cardiovascular disease (CVD). Chronic low-grade immune activation is likely one of the driving mechanisms. This systematic review provides an overview of the evidence addressing the relation
Alinda G Vos, Annelieke Hulzebosch, Diederick E Grobbee, Roos E Barth, Kerstin Klipstein-Grobusch   +4 more
doaj   +1 more source

Novel Surrogate Markers of CNS Inflammation in CSF in the Diagnosis of Autoimmune Encephalitis

Frontiers in Neurology, 2020
Background: Autoimmune encephalitis (AE) is an important cause of refractory epilepsy, rapidly progressive cognitive decline, and unexplained movement disorders in adults.
Jocelyn X. Jiang, Jocelyn X. Jiang, Jocelyn X. Jiang, Nicole Fewings, Suat Dervish, Alessandro F. Fois, Alessandro F. Fois, Stephen R. Duma, Stephen R. Duma, Matthew Silsby, Matthew Silsby, Sushil Bandodkar, Sushil Bandodkar, Sudarshini Ramanathan, Sudarshini Ramanathan, Sudarshini Ramanathan, Andrew Bleasel, Andrew Bleasel, Bryne John, David A. Brown, David A. Brown, David A. Brown, Ming-Wei Lin, Ming-Wei Lin, Ming-Wei Lin   +24 more
doaj   +1 more source

Surrogate markers in HIV disease [PDF]

Journal of Antimicrobial Chemotherapy, 1996
The use of surrogate markers in HIV disease is an attractive method of assessing the efficacy of new treatments more quickly than by using clinical end-points. The characteristics of an ideal surrogate marker and the theoretical dangers of extrapolating properties from one class of drug to another are described.
openaire   +2 more sources