Results 191 to 200 of about 59,334 (307)

Full-field surrogate modeling of cardiac electrophysiology encoding geometric variability. [PDF]

Comput Methods Appl Mech Eng
Martinez ES, Moscoloni B, Salvador M, Kong F, Peirlinck M, Marsden AL.   +5 more
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

RBF-assisted surrogate modeling and machine learning for mechanical property prediction in friction stir additive manufacturing: Application to dissimilar AA6061/AA7075 aluminum alloys. [PDF]

Sci Rep
Venkatachalam K, Selvaraj SK, Mannayee G, Pattabiraman K, G S.   +4 more
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Surrogate modeling for time-dependent reliability analysis of robotic manipulator trajectories. [PDF]

PLoS One
Ayoob K, Elahi H, Zafar T, Hamza A, Wang Z.   +4 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Optimization of the grid-stiffened structure via PSO-LSSVR surrogate modeling and sensitivity analysis. [PDF]

Sci Rep
Gai J, Jian Y, Deng Q, Wang J, Zheng M, Yang Y.   +5 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Kriging based Surrogate Modeling for Fractional Order Control of Microgrids

, 2014
This paper investigates the use of fractional order (FO) controllers for a microgrid. The microgrid employs various autonomous generation systems like wind turbine generator (WTG), solar photovoltaic (PV), diesel energy generator (DEG) and fuel-cells (FC)
I Pan (21875285), S Das (7803908)
core  

Hybrid Multimodal Surrogate Modeling and Uncertainty-Aware Co-Design for L-PBF Ti-6Al-4V with Nanomaterials-Informed Morphology Proxies. [PDF]

Nanomaterials (Basel)
Hossain RB, Pan X, Chang G, Su X, Tao Y, Han X.   +5 more
europepmc   +1 more source