Results 181 to 190 of about 59,334 (307)

Experiment-Driven Gaussian Process Surrogate Modeling and Bayesian Optimization for Multi-Objective Injection Molding. [PDF]

Polymers (Basel)
Omar HM, Mukras SMS.
europepmc   +1 more source

Efficient Surrogate Modeling and Design Optimization of Compact Integrated On-Chip Inductors Based on Multi-Fidelity EM Simulation Models. [PDF]

Micromachines (Basel), 2021
Kurgan P.
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Deep adaptive sampling for surrogate modeling without labeled data

Surrogate modeling is of great practical significance for parametric differential equation systems. In contrast to classical numerical methods, using physics-informed deep learning methods to construct simulators for such systems is a promising direction
Tang, Kejun, Zhai, Jiayu, Wan, Xiaoliang, Yang, Chao, Wang, Xili   +4 more
core   +1 more source

Genetic algorithm-based optimization of columella shape with FEM surrogate modeling: convergence analysis and application to ossicular chain reconstruction. [PDF]

Biomech Model Mechanobiol
Asakura T, Ozono K, Ichino T, Hirabayashi M, Kurihara S, Kurashina Y.   +5 more
europepmc   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Surrogate modeling techniques applied to energy systems

, 2011
Verkefnið er unnið í tengslum við Háskóla Íslands og Háskólann á AkureyriThis Master Thesis investigates the possibility of using the surrogate modeling techniques in the complex energy system modeling problems.
Sciazko, Anna
core  

Advances in surrogate modeling for biological agent-based simulations: trends, challenges, and future prospects. [PDF]

J Math Biol
Norton KA, Bergman D, Jain HV, Jackson T.   +3 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source