Results 61 to 70 of about 456,731 (293)

Uncertainty quantification of surrogate models using conformal prediction

Machine Learning: Science and Technology
Data-driven surrogate models offer fast, inexpensive approximations to complex numerical and experimental systems but typically lack uncertainty quantification, limiting their reliability in safety-critical applications.
Vignesh Gopakumar, Ander Gray, Joel Oskarsson, Lorenzo Zanisi, Daniel Giles, Matt J Kusner, Stanislas Pamela, Marc Peter Deisenroth   +7 more
doaj   +1 more source

Multi-Objective Optimization of Building Energy Consumption: A Case Study of Temporary Buildings on Construction Sites

Buildings
Building energy consumption management significantly impacts energy efficiency, environmental effects, and economic benefits throughout a building’s life cycle.
Xiaohui Guo, Yuanfeng Wang, Yinshan Liu, Lei Fan, Shaoqin Xue, Chengcheng Shi, Lei Pan, Boqun Zhang, Liping Wang, Xinlei Chang   +9 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

NNVA: Neural Network Assisted Visual Analysis of Yeast Cell Polarization Simulation

, 2019
Complex computational models are often designed to simulate real-world physical phenomena in many scientific disciplines. However, these simulation models tend to be computationally very expensive and involve a large number of simulation input parameters
Chou, Ching-Shan, Hazarika, Subhashis, Li, Haoyu, Shen, Han-Wei, Wang, Ko-Chih   +4 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Learning Surrogate Models of Document Image Quality Metrics for Automated Document Image Processing

, 2017
Computation of document image quality metrics often depends upon the availability of a ground truth image corresponding to the document. This limits the applicability of quality metrics in applications such as hyperparameter optimization of image ...
Hast, Anders, Singh, Prashant, Vats, Ekta   +2 more
core   +1 more source

mfEGRA: Multifidelity Efficient Global Reliability Analysis through Active Learning for Failure Boundary Location

, 2020
This paper develops mfEGRA, a multifidelity active learning method using data-driven adaptively refined surrogates for failure boundary location in reliability analysis.
Chaudhuri, Anirban, Marques, Alexandre N., Willcox, Karen E.   +2 more
core   +1 more source

Convergence of Weak-SINDy Surrogate Models

SIAM Journal on Applied Dynamical Systems
In this paper, we give an in-depth error analysis for surrogate models generated by a variant of the Sparse Identification of Nonlinear Dynamics (SINDy) method. We start with an overview of a variety of non-linear system identification techniques, namely, SINDy, weak-SINDy, and the occupation kernel method.
Benjamin P. Russo, M. Paul Laiu
openaire   +3 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Point-Wise Full-Field Physics Neural Mapping Framework via Boundary Geometry Constrained for Large Thermoplastic Deformation

Algorithms
Computation modeling for large thermoplastic deformation of plastic solids is critical for industrial applications like non-invasive assessment of engineering components.
Jue Wang, Xinyi Xu, Changxin Ye, Wei Huangfu   +3 more
doaj   +1 more source