Results 41 to 50 of about 479,017 (202)

FUS-CHOP promotes invasion in myxoid liposarcoma through a SRC/FAK/RHO/ROCK-dependent pathway [PDF]

open access: yes, 2017
Deregulated SRC/FAK signaling leads to enhanced migration and invasion in many types of tumors. In myxoid and round cell liposarcoma (MRCLS), an adipocytic tumor characterized by the expression of the fusion oncogene FUS-CHOP, SRC have been found as one ...
González, M. Victoria   +3 more
core   +2 more sources

Research on Rock Burst Control Mechanism of Deep Buried Tunnel Using Surrounding Rock Modification Theory

open access: yesShock and Vibration, 2022
In order to solve the rock burst disaster during the excavation of deep buried high stress hard rock tunnel, the method of changing the properties of surrounding rock by blasting is proposed in this paper. This method can effectively change the physical and mechanical properties of surrounding rock, reduce the storage capacity of surrounding rock ...
Yanhua Sun, Xiaohu Zhang, Hanhua Xu
openaire   +2 more sources

Damage evolution and failure warning in early-age flexible-formwork concrete for underground support

open access: yesGeohazard Mechanics
The evolution law of mechanical properties and damage characteristics of early-age flexible formwork filling concrete have a decisive influence on the stability control of surrounding rock of large deformation roadway.
Zijun Han   +7 more
doaj   +1 more source

Instability Mechanism and Key Control Technology of Deep Soft Rock Roadway under Long-Term Water Immersion

open access: yesAdvances in Civil Engineering, 2021
More and more attention has been paid to the supporting problem of deep soft rock roadway floor with long-term water immersion in recent years. However, the existing soft rock roadway support technology rarely takes into account the influence of the ...
Wei Jing   +4 more
doaj   +1 more source

Mechanism of rock burst in deep coal tunnel surroundings due to three-way stress difference gradient

open access: yesMeitan xuebao, 2023
With the deep coal tunnel surrounding rock as the research object, in view of the serious rock burst hazards, incomplete rock burst mechanism research, and the lack of more targeted guidance on the prevention and control of rock burst engineering, indoor
Guolei LIU   +5 more
doaj   +1 more source

Mapping of landslide susceptibility of coastal cliffs : the Mont-Roig del Camp case study [PDF]

open access: yes, 2012
The weathered and fractured conglomerate cliffs of Mont Roig del Camp constitute a rock fall hazard for the surrounding pocket beaches and, therefore, for the population that frequent them, especially over the summer.
Alcántara-Carrió, Javier   +6 more
core   +3 more sources

ROCK2/rasHa cooperation induce malignant conversion via p53 loss, elevated NF-κβ and tenascin C-associated rigidity but p21 inhibits ROCK2/NF-κβ-mediated progression [PDF]

open access: yes, 2017
To study ROCK2 activation in carcinogenesis, mice expressing 4-hydroxytamoxifen (4HT)- activated ROCK2 [K14.ROCKer] were crossed to mice expressing epidermal activated ras Ha [HK1.ras1205].
Greenhalgh, D.A.   +3 more
core   +1 more source

An efficient, economical slow-freezing method for large-scale human embryonic stem cell banking [PDF]

open access: yes, 2012
Human embryonic stem cells (hESCs) are one of the most interesting cell types for tissue engineering, cell therapy, basic scientific research, and drug screening. Fast advancement in these areas requires the availability of large amounts of safe and well-
Cornelissen, Maria   +3 more
core   +2 more sources

Research progress of support theory and technology of the roadway surrounding rock based on the plastic zone control

open access: yesMeitan xuebao
With the increasing depth of coal mining, the stability control of surrounding rock in deep roadway has become one of major problems in the mining field, and the effect of surrounding rock control in deep roadway is directly related to the safe ...
Weijun WANG   +3 more
doaj   +1 more source

Research on the stability control of surrounding rock in the roadway with dynamic pressure and high slope

open access: yesGong-kuang zidonghua, 2021
The roadway with dynamic pressure and high slope refers to the roadway which is seriously affected by dynamic pressure and has a high slope. This type of roadway not only experiences disturbances in the excavation process, but also has to experience the ...
SHEN Binxue   +5 more
doaj   +1 more source

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