Results 61 to 70 of about 480,494 (299)

Stress Relief and Support for Stability of Deep Mining Roadway with Thick Top Coal in Hujiahe Coal Mine with the Risk of Rock Burst

Shock and Vibration, 2021
Rock burst is a typical dynamic disaster in deep underground coal mining. Based on the support problems of the deep roadways in fully mechanized caving face 401111 of Hujiahe Coal Mine suffering from rock burst in Shaanxi Province of China, the failure ...
Wenjing Liu, Deyu Qian, Xingguo Yang, Sujian Wang, Jinping Deng, Qi Cui, Zexiang Li   +6 more
doaj   +1 more source

Preliminary Canopy Removal Experiments in Algal Dominated Communities Low on the Shore and in the Shallow Subtidal on the Isle of Man [PDF]

, 1985
The algal dominated communities immediately above and below the low-water spring level on a moderately exposed Manx shore were investigated by canopy removal experiments. Fucus serratus, Laminaria digitata and L. hyperborea were removed.
Dayton P. K., Harkin E., Hawkins S. J., Kain J. M, Kastendiek J., Southward A. J.   +5 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Large scale gas injection test (Lasgit) performed at the Äspö Hard Rock Laboratory: summary report 2007 [PDF]

, 2008
The deposition hole was closed on the 1st February 2005 signifying the start of the hydration phase. Groundwater inflow through a number of conductive discrete fractures resulted in elevated porewater pressures leading to the formation of conductive ...
Birchall, D.J., Cuss, R.J., Harrington, J.F., Noy, D.J.   +3 more
core  

An efficient, economical slow-freezing method for large-scale human embryonic stem cell banking [PDF]

, 2012
Human embryonic stem cells (hESCs) are one of the most interesting cell types for tissue engineering, cell therapy, basic scientific research, and drug screening. Fast advancement in these areas requires the availability of large amounts of safe and well-
Cornelissen, Maria, De Grande, Linde, Declercq, Heidi, T'Joen, Veronique   +3 more
core   +2 more sources

Tunnel Surrounding Rock Deformation Characteristics and Control in Deep Coal Mining

Geomaterials, 2013
In order to study the failure characteristics and control method of deep tunnel surrounding rock, based on the stress test, the structure and stress state of the main transportation tunnel surrounding rock in Mine Zhaogezhuang level 14 was analyzed, and it shows that the surrounding rock is exposed to an interphase hard and soft disadvantageous ...
Zhiqiang Zhao, Housheng Jia, Bo Peng, Yangyang Dong   +3 more
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Research Progress on Safety Control of Surrounding Rock-Support System in Deep Buried Soft Rock Tunnels

IOP Conference Series: Earth and Environmental Science, 2021
Abstract The deep-buried soft rock tunnel has large deformation degree and long duration, which makes the surrounding rock-support very difficult. How to formulate effective design countermeasures to control soft rock deformation is one of the important technical problems in the design and construction of deep-buried soft rock tunnels ...
Jianhe Li, Wanmin You, Song Wu, Jian Li, Jian Han   +4 more
openaire   +1 more source