Results 61 to 70 of about 33,130 (261)

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

Advanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang, Henry Robert Howard, Shihui Chen, Won‐Young Choi, Summer Cao, Arthur Chien, Kevin Zou, Michael Kassiou, Fabien Delerue, Ho Sang Jung, Yeonju Park, Young Mee Jung, Yong‐Dae Kwon, Karrie M. Kiang, Gilberto Ka‐Kit Leung, Ryohichi Sugimura, Ann‐Na Cho, Sang Jin Lee   +17 more
wiley   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

Study on Failure Characteristics and Rock Burst Mechanism of Roadway Roof under Cyclic Dynamic Load

Shock and Vibration, 2021
Rock burst is a catastrophic phenomenon that often occurs in underground rock mass engineering. In order to reveal the essence of rock burst of a hard roof in the process of roadway excavation, the particle discrete element method is used to establish a ...
Chunmei Zheng, Jiayan Zheng, Xiaojuan Peng, Lei Zhou   +3 more
doaj   +1 more source

Mechanotransduction of Magnetically Applied Forces Leads to Mechanical Stiffening of Platelet‐Rich Plugs

Advanced Healthcare Materials, EarlyView.
A microfluidic device with magnetic microposts was used to assess platelet mechanobiology. The oscillatory actuation of posts with embedded iron particles was dampened by the dynamic stiffening of the platelet‐rich plugs. This stiffening process increased with applied load, but inhibiting platelet activation (ASA) or myosin contractility (blebbistatin)
Nikita Taparia, Ava M. Obenaus, Yoeur‐Man T. Mach, Nakul Sridhar, Nathan J. Sniadecki   +4 more
wiley   +1 more source

Optimization of Control Measures for Rock Mass Disturbed by Repeated Tunnel Repairs and Engineering Practice

Infrastructures
To address the difficulty of controlling surrounding rock subjected to repeated repair-induced disturbances, the characteristics of the roadway surrounding rock and its deformation–failure mechanisms were examined.
Zenghui Liu, Minjun Chen
doaj   +1 more source

Ferroelectric Quantum Dots for Retinomorphic In‐Sensor Computing

Advanced Materials, EarlyView.
This work has provided a protocol for fabricating retinomorphic phototransistors by integrating ferroelectric ligands with quantum dots. The resulting device combines ferroelectricity, optical responsiveness, and low‐power operation to enable adaptive signal amplification and high recognition accuracy under low‐light conditions, while supporting ...
Tingyu Long, Huanyu Zhou, Jaewan Ko, Hongwei Tan, Jaemin Lim, Yanfei Zhao, Daehan Kang, Eojin Yoon, Gyeong‐Tak Go, Somin Kim, Seung‐Woo Lee, Chan‐Yul Park, Hyojun Choi, Hyeran Kim, Hyung Joong Yun, Sung Hyuk Park, Kwan Sik Park, Jeong Woo Park, Mungeun Kim, Yong Soo Cho, Ho Won Jang, Wenqiang Yang, Min Hyuk Park, Wan Ki Bae, Sebastiaan van Dijken, Joona Bang, Tae‐Woo Lee   +26 more
wiley   +1 more source

Opportunities of Semiconducting Oxide Nanostructures as Advanced Luminescent Materials in Photonics

Advanced Materials, EarlyView.
The review discusses the challenges of wide and ultrawide bandgap semiconducting oxides as a suitable material platform for photonics. They offer great versatility in terms of tuning microstructure, native defects, doping, anisotropy, and micro‐ and nano‐structuring. The review focuses on their light emission, light‐confinement in optical cavities, and
Ana Cremades, Pedro Hidalgo, David Maestre, Ruth Martínez‐Casado, Emilio Nogales, Beatriz Rodríguez, G. Cristian Vásquez, Bianchi Méndez   +7 more
wiley   +1 more source

The effect of burnt rock on inclined shaft in shallow coal seam and its control technology

Energy Science & Engineering, 2019
Burnt rock is a geo‐material widely existed in many countries. After the rock mass is burned, the fracture is developed, the structure is destroyed, the integrity and strength are reduced, and a good water storage space is formed in suitable hydration ...
Yong Yuan, Zhi‐Heng Liu, Cheng Zhu, Chao‐Feng Yuan, Sheng‐Zhi Wang   +4 more
doaj   +1 more source

Research and application of pre-stressed continuous surrounding rock control technology

Meikuang Anquan, 2021
Pre-stressed continuous surrounding rock control technology was proposed to solve the problem of serious deformation and destruction of the return air lane of No. 5 working face of Ⅱ2-1 coal in Lingdong Mine. First of all, the mechanical model of the anchor bolt pre-stress transfer in the surrounding rock was established through theoretical analysis ...
WAN Feng, WANG Zhanling, ZHANG Hongqing, FAN Mingjian, YAN Shouqing, GUO Gangye   +5 more
openaire   +1 more source

Stability of Close Chambers Surrounding Rock in Deep and Comprehensive Control Technology

Advances in Civil Engineering, 2018
The purpose of this paper is to solve the problem that deep and close‐distance cavern and roadway group were easily affected by the adjacent chamber or roadway excavation disturbance and low stability and significant deformation of surrounding rock occurred.
Weijian Yu, Fangfang Liu
openaire   +2 more sources