Results 91 to 100 of about 1,413,891 (296)

Fabrication and loading of long-term stress corrosion cracking surveillance specimens for the Dresden 1 decontamination program [PDF]

open access: yes, 1979
Stress-corrosion cracking test specimens were prepared for Dow Nuclear Services for insertion in the Dresden 1 reactor during the chemical decontamination of the primary system, and for subsequent exposure under operating conditions when the station returns to service.
openaire   +2 more sources

MCSS – program of neutron transport calculation to location of surveillance specimens in reactor VVER-1000. Variance reduction scheme

open access: yesNuclear Physics and Atomic Energy, 2002
The necessity of development of the variance reduction scheme for usage in MCSS program is well grounded. The criterions of nonanalog method selection are stated. The most important elements of the developed scheme are described. Opportunities of numerous problems solution by usage of this scheme and opportunities of expanding its applicability are ...
O.V. Grytsenko   +2 more
openaire   +1 more source

Weekly Influenza Surveillance Report Weeks 51 & 52 2002

open access: yes, 2003
The sentinel GP consultation rate for influenza-like illness remains at low levels. Influenza virus has not been detected this season in sentinel or non-sentinel specimens.
National Disease Surveillance Centre (NDSC)   +2 more
core  

EBV‐Driven ODC1 Upregulation Enhances Polyamine Anabolism to Promote Viral Replication and Cisplatin Resistance in Nasopharyngeal Carcinoma

open access: yesAdvanced Science, EarlyView.
EBV‑BZLF1 initiates ODC1‑driven polyamine anabolism that correlates with poor clinical prognosis in nasopharyngeal carcinoma. The ODC1–spermidine axis promotes viral replication, cell proliferation and innate immune evasion. Pharmacological inhibition of ODC1 rescues cisplatin sensitivity, establishing ODC1 as a viable therapeutic target for EBV ...
Yueshuo Li   +9 more
wiley   +1 more source

Weekly Influenza Surveillance Report Week 41 2003

open access: yes, 2003
The first positive cases of influenza virus (4 influenza A H3N2) reported through the GP sentinel surveillance scheme for the 2003/2004 season were identified in week 41.
National Disease Surveillance Centre (NDSC)   +2 more
core  

Tissue‐Agnostic Cellular Morphometric Biomarkers for Risk‐Adapted Management Across Gastrointestinal Precancerous Lesions and Cancers

open access: yesAdvanced Science, EarlyView.
An interpretable, unsupervised artificial intelligence framework identifies a 13‐cellular morphometric biomarker (CMB) signature from routine H&E whole‐slide images. Validated across 2,602 patients, the fixed signature generalizes across colorectal, gastric, and esophageal tissues without retraining, stratifies prognosis and precancerous lesion risk ...
Pin Wang   +14 more
wiley   +1 more source

European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender

open access: yesBJS (British Journal of Surgery), EarlyView., 2020
Recommendations for clinical and molecular identification of LS, surgical and endoscopic management of LS‐associated colorectal cancer and preventive measures for cancer were produced. The emphasis was on surgical and gastroenterological aspects of the cancer spectrum.
T. T. Seppälä   +18 more
wiley   +1 more source

Weekly Influenza Surveillance Report Week 44 2002 [PDF]

open access: yes, 2002
To date, no laboratory confirmed cases of influenza have been identified during the 2002/2003-influenza season. There has been an increase in the number of positive RSV specimens from non-sentinel sources this season compared to the 2001/2002- influenza ...
National Disease Surveillance Centre (NDSC)   +2 more
core  

Deubiquitination of Vangl by USP6 and USP32 Regulates Planar Cell Polarity Signaling

open access: yesAdvanced Science, EarlyView.
Compartment‐specific deubiquitination controls Vangl dosage and planar cell polarity signaling. USP6 and USP32 regulate distinct subcellular pools of Vangl by removing distinct ubiquitin modifications from Vangl proteins. This regulatory mechanism safeguards PCP‐dependent embryonic morphogenesis, while aberrant USP32‐dependent stabilization of VANGL ...
Fangzi Zha   +13 more
wiley   +1 more source

NSUN2‐Mediated m5C Modification of TGFB1 in Trophoblasts Remodels Macrophage Function to Prevent URSA

open access: yesAdvanced Science, EarlyView.
NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu   +10 more
wiley   +1 more source

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