Results 51 to 60 of about 2,418,550 (336)

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

open access: yesMolecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo   +8 more
wiley   +1 more source

Predictors of late presentation and advanced HIV disease among people living with HIV in Oman (2000–2019)

open access: yesBMC Public Health, 2021
Background The aim of this study was to determine the proportions and predictors of late presentation (LP) and advanced HIV disease (AD) in Oman. LP and AD were defined as presenting with a baseline CD4 count of
Ali Elgalib   +8 more
doaj   +1 more source

Event-based surveillance during EXPO Milan 2015. Rationale, tools, procedures, and initial results [PDF]

open access: yes, 2016
More than 21 million participants attended EXPO Milan from May to October 2015, making it one of the largest protracted mass gathering events in Europe.
Bastiampillai, Anan Judina   +14 more
core   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

open access: yesMolecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima   +6 more
wiley   +1 more source

Association between frailty and mortality among patients with accidental hypothermia: a nationwide observational study in Japan

open access: yesBMC Geriatrics, 2021
Background Frailty has been associated with a risk of adverse outcomes, and mortality in patients with various conditions. However, there have been few studies on whether or not frailty is associated with mortality in patients with accidental hypothermia
Shuhei Takauji   +18 more
doaj   +1 more source

Surveillance and monitoring [PDF]

open access: yesObesity Reviews, 2007
Background: The UK Government has identified obesity as a priority area, as it is thought to present a serious public health problem. Although it is a highly complex multifactorial disease, it has been hypothesized that obesity, in particular morbid obesity, may decrease life by up to 9 years and significantly increase the risk of many other ...
Wilkinson, J. R.   +3 more
openaire   +4 more sources

The Emergence of Big Data Policing [PDF]

open access: yes, 2017
The past decade has seen both the proliferation of surveillance in everyday life and the rise of “big data.” Through extensive qualitative research focusing on the Los Angeles Police Department (LAPD), PRC faculty research associate Sarah Brayne explores
Brayne, Sarah
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Everyday Surveillance [PDF]

open access: yesProceedings of the 2016 CHI Conference Extended Abstracts on Human Factors in Computing Systems, 2016
Surveillance, literally the 'close watching over' of a person or a group, was historically carried out to monitor adversaries and criminals. The digital era of sensor-rich, connected devices means that new forms of everyday surveillance -- what some are calling 'dataveillance' -- are emerging.
Briggs, Pam   +5 more
openaire   +2 more sources

Alpha-fetoprotein detection of hepatocellular carcinoma leads to a standardized analysis of dynamic AFP to improve screening based detection [PDF]

open access: yes, 2016
Detection of hepatocellular carcinoma (HCC) through screening can improve outcomes. However, HCC surveillance remains costly, cumbersome and suboptimal. We tested whether and how serum Alpha-Fetoprotein (AFP) should be used in HCC surveillance.
Ahn, Sang Hoon   +11 more
core   +3 more sources

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