Results 161 to 170 of about 1,617,498 (307)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
A nation of caregivers: past, present, and future expectations of caregiving. [PDF]
Health Aff SchMiller KEM +4 more
europepmc +1 more source
Non-Fundamental Expectations and Economic Fluctuations: Evidence from Professional Forecasts [PDF]
It is theoretically possible that non-fundamental idiosyncratic shocks to agents’ rational expectations are a source of economic fluctuations. Studies using data on consumer and investor sentiment suggest that this is indeed a significant source of ...
Anthony S. Tay +2 more
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Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Utopia becoming dystopia? Analyzing political trust among immigrants in Sweden [PDF]
This paper aims to increase our knowledge on the political trust of immigrants’ in established democracies. Utilising Swedish survey data, based on a large oversample of respondents with a foreign background, we show that immigrants from countries more ...
Adman, Per, Strömblad, Per
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
The Impact of Societal Ageing on Individual Consumers' Insurance Purchase Intentions: A Review and Research Agenda. [PDF]
Behav Sci (Basel)Bangaan Abdullah MH +3 more
europepmc +1 more source
How Should We Measure Consumer Confidence (Sentiment)? Evidence from the Michigan Survey of Consumers [PDF]
The Michigan Index of Consumer Sentiment (ICS) and other indices of consumer confidence are prominent in public discourse on the economy but have little presence in modern economic research.
Charles F. Manski, Jeff Dominitz
core
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Filial piety and fertility decisions, Thailand. [PDF]
Bull World Health OrganWitvorapong N, Stankovich J, Zin T.
europepmc +1 more source