Results 121 to 130 of about 97,135 (282)

Features of Organizational and Technical Measures to Increase the Level of Survivability and Explosion and Fire Safety of Potentially Dangerous Objects

Nauka ta progres transportu
Purpose. The work is aimed at studying the peculiarities of organizational and technical measures to improve the level of explosion and fire safety of potentially dangerous objects. Methodology.
V. V. Onishchenko, S. M. Sukhai
doaj   +1 more source

Robust Energy Management for Green and Survivable IP Networks [PDF]

, 2013
Despite the growing necessity to make Internet greener, it is worth pointing out that energy-aware strategies to minimize network energy consumption must not undermine the normal network operation.
Addis, Bernardetta, Capone, Antonio, Carello, Giuliana, Gianoli, Luca G., Sansò, Brunilde   +4 more
core   +2 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Survivability Protection in TWDM Optical Access Network with Dynamic Wavelength Scheduling

Dianxin kexue, 2015
It is a key technical problem to locate failure correctly and perform protection switching for strong survivability in time and wavelength division multiplexing（TWDM）optical access network with dynamic wavelength scheduling. To solve the above problem, a
Xintian Hu, Zhiguo Zhang, Xue Chen
doaj  

Effect of different stocking densities on growth performance, feed utilization, and survival of Labeo angra (Hamilton) fry in aquaria

Fisheries & Aquatic Life
This study was conducted to assess the effect of stocking density on the growth performance, feed utilization, and survival of Labeo angra (Hamilton) in nine glass aquaria each containing 30 l of water for 45 days. Three different stocking densities of 1,
Akhtaruzzaman, Nahid Akter Mst., Ali Azhar, Saha Srebash Kumar, Dorin Moumita Habiba Sarmin   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

An Algorithm for Identifying the Possibilities of Cascading Failure Processes and Their Development Trajectories in Electric Power Systems

Algorithms
Every year, electric power systems (EPSs) experience accidents resulting in static and dynamic instability, as well as power supply disruptions. Accidents evolve along various trajectories and sometimes can exhibit a cascading effect.
Pavel Ilyushin, Bulat Gaisin, Ildar Shahmaev, Konstantin Suslov   +3 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source