Results 131 to 140 of about 7,054,284 (355)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Nature connectedness and conservation representations among zoo professionals: an exploratory case study

Frontiers in Psychology
Zoological parks with conservation missions must reconcile commercial sustainability with conservation goals within hybrid organizational structures, making employees’ nature connectedness and conservation meaning-making potentially important for ...
Joao Neves, Joao Neves, Edgar Ribeiro, Edgar Ribeiro, Isa Pinho, Isa Pinho   +5 more
doaj   +1 more source

Surviving [PDF]

Journal of Oncology Practice, 2009
openaire   +2 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Developing the frameworks to establish model referral networks for emergency obstetric care in Haiti

Annals of Global Health, 2016
Megan Lydon, Emmanuel Louis, Emmanuel Salnave, Rachel Coq, Lucito Jeannis, Blami Dao, Jessica Thimm, Bethany Arnold   +7 more
doaj   +1 more source

A STUDY ON COMPRESSIVE FATIGUE STRENGTH OF CONCRETE CONSIDERED SURVIVAL PROBABILITY

, 1979
Hiromichi Matsushita, Yoshiharu Tokumitsu   +1 more
openalex   +2 more sources

Surviving survival analysis [PDF]

Bone Marrow Transplantation, 2001
openaire   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Clinicopathological characteristics and prediction of cancer-specific survival in large cell lung cancer: a population-based study [PDF]

, 2020
Yafei Shi, Wei Chen, Chunyu Li, Shuya Qi, Xiaowei Zhou, Yujun Zhang, Ying Li, Guohui Li   +7 more
openalex   +1 more source