Results 171 to 180 of about 8,796,658 (382)

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Distribution of Abnormal Hemoglobins in Puerto Rico and Survival Studies of Red Blood Cells Using Cr51 [PDF]

, 1959
R. M. Suárez, R. Buso, Leo M. Meyer, S. T. OLAVARRIETA   +3 more
openalex   +1 more source

Surviving survival analysis [PDF]

Bone Marrow Transplantation, 2001
openaire   +1 more source

Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma

New England Journal of Medicine, 2017
J. Wolchok, V. Chiarion-Sileni, R. Gonzalez, P. Rutkowski, J. Grob, L. Cowey, C. Lao, J. Wagstaff, D. Schadendorf, P. Ferrucci, M. Smylie, R. Dummer, A. Hill, D. Hogg, J. Haanen, M. Carlino, O. Bechter, M. Maio, I. Márquez-Rodas, M. Guidoboni, G. McArthur, C. Lebbé, P. Ascierto, G. Long, J. Cebon, J. Sosman, M. Postow, M. Callahan, D. Walker, L. Rollin, R. Bhore, S. Hodi, J. Larkin   +32 more
semanticscholar   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Developing the frameworks to establish model referral networks for emergency obstetric care in Haiti

Annals of Global Health, 2016
Megan Lydon, Emmanuel Louis, Emmanuel Salnave, Rachel Coq, Lucito Jeannis, Blami Dao, Jessica Thimm, Bethany Arnold   +7 more
doaj   +1 more source

Survival time and critical temperatures of various strains of Entamoeba histolytica [PDF]

, 1958
Hugo Álvarez-Argüelles Cabrera, Richard Porter   +1 more
openalex   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

The relation of oxygen to the survival metabolism of muscle [PDF]

, 1902
W. M. Fletcher
openalex   +1 more source