Results 231 to 240 of about 8,796,658 (382)

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source

Demographic and clinical predictors of treatment outcomes in invasive lobular carcinoma breast cancer: insights from Cox regression analysis. [PDF]

Discov Oncol
Kaindal S, Venkataramana B.
europepmc   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

Imaging-derived biomarkers from ⁶⁸Ga-DOTATOC PET/CT scans to predict survival of patients with neuroendocrine tumors after PRRT with ¹⁷⁷Lu-DOTATATE. [PDF]

Cancer Imaging
Raad S, Al-Fatlawi A, Wise CL, Fottner C, Schadmand-Fischer S, Schreckenberger M, Weber MM, Musholt TJ, Schroeder M, Miederer M.   +9 more
europepmc   +1 more source

Survival of Enteric Organisms in Sea Water: A Review of the Literature [PDF]

, 1956
Arnold E. Greenberg
openalex   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

Collaborative national satellite event of World Species Congress for conservation in Indonesia

Oryx
Celia Nova Felicity, Mirza Dikari Kusrini, Sunarto Sunarto   +2 more
doaj   +1 more source

Survival days of patients with metastatic spinal tumors of lung cancer requiring surgery: a prospective multicenter study. [PDF]

Sci Rep
Takahashi T, Hirai T, Shiratani Y, Suzuki A, Kakutani K, Kato S, Tominaga H, Inoue H, Sawada H, Takegami N, Nakanishi K, Nakajima H, Ishihara M, Oshigiri T, Funayama T, Iimura T, Tanishima S, Nakashima H, Yamabe D, Hashimoto K, Uotani K, Funaba M, Nagoshi N, Kobayakawa K, Yoshii T, Watanabe K, Nakamae T, Kaito T, Inoue G, Imagama S, Watanabe K, Furuya T.   +31 more
europepmc   +1 more source

AN ANALYTICAL STUDY OF IN VIVO SURVIVAL OF LIMITED POPULATIONS OF ANIMAL RED BLOOD CELLS TAGGED WITH RADIOIRON [PDF]

, 1953
Ivan W. Brown, G. S. Eadie
openalex   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source