Results 71 to 80 of about 28,926,907 (345)
Frontiers in NeurologyObjectiveWe introduce the comprehensive inflammatory prognostic index (CIPI), a novel prognostic tool for critically ill cerebral infarction patients, designed to meet the urgent need for timely and convenient clinical decision-making in this high-risk ...
Chang Shu, Chenguang Zheng, Guobin Zhang
doaj +1 more source
Cancer Medicine, 2022 Background The relationship between metastatic colorectal cancer (mCRC) and venous thromboembolism (VTE) is poorly defined in the modern era. Our objective was to examine impact of putative risk factors including newer treatments and anti‐angiogenic ...
Steven Ades +5 more
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Cost-effectiveness analysis in R using a multi-state modelling survival analysis framework: a tutorial [PDF]
, 2016 This tutorial provides a step-by-step guide to performing cost-effectiveness analysis using a multi-state modelling approach. Alongside the tutorial we provide easy-to-use functions in the statistics package R.
Briggs, Andrew H. +3 more
core +2 more sources
Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1
FEBS Letters, EarlyView.Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji +5 more
wiley +1 more source
Time‐to‐event prediction using survival analysis methods for Alzheimer's disease progression
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2021 Introduction Many research studies have well investigated Alzheimer's disease (AD) detection and progression. However, the continuous‐time survival prediction of AD is not yet fully explored to support medical practitioners with predictive analytics.
Rahul Sharma +3 more
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Determinants of healthcare utilisation and predictors of outcome in colorectal cancer patients from Northern Iran [PDF]
, 2016 We aimed to assess healthcare utilisation (HU), its determinants, as well as its relationship with survival in colorectal cancer (CRC) patients. This study was conducted on incident CRC cases from Northern Iran.
Aryaie, M. +8 more
core
The role of fibroblast growth factors in cell and cancer metabolism
FEBS Letters, EarlyView.Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source
High-Intensity Focused Ultrasound Ablation of Prostate Cancer: 15 Years of Follow-up
Креативная хирургия и онкология, 2023 Introduction. Prostate cancer (PC) is considered to be one of the most common malignancies in men. In recent years, conventional PC treatments have been supplemented with highly effective minimally invasive therapies such as highintensity focused ...
V. A. Solovov, A. A. Tiurin
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Impact of an interatrial shunt device on survival and heart failure hospitalization in patients with preserved ejection fraction [PDF]
, 2019 Aims: Impaired left ventricular diastolic function leading to elevated left atrial pressures, particularly during exertion, is a key driver of symptoms and outcomes in heart failure with preserved ejection fraction (HFpEF). Insertion of an interatrial
Aytug, H +22 more
core +2 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source