Results 71 to 80 of about 4,736,557 (326)
Pretreatment prognostic value of dynamic contrast-enhanced magnetic resonance imaging vascular, texture, shape, and size parameters compared with traditional survival indicators obtained from locally advanced breast cancer patients [PDF]
, 2015 Objectives: The aim of this study was to determine if associations exist between pretreatment dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI)-based metrics (vascular kinetics, texture, shape, size) and survival intervals.
Gibbs, Peter +2 more
core +1 more source
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Heterogeneous Datasets for Federated Survival Analysis Simulation [PDF]
arXiv, 2023 Survival analysis studies time-modeling techniques for an event of interest occurring for a population. Survival analysis found widespread applications in healthcare, engineering, and social sciences. However, the data needed to train survival models are often distributed, incomplete, censored, and confidential.
arxiv
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018 Background 8‐Oxo‐2′‐deoxyguanosine (8‐oxo‐2′‐dG) is a biomarker of oxidative DNA damage that is associated with cardiovascular disease and premature mortality in the general population.
Merlin C. Thomas +9 more
doaj +1 more source
Infectio, 2021 Objective: to describe the seven-year survival and predictors of mortality among people with HIV who were treated in the Colombian health system between 2011 and 2018.Methods: 64 039 people diagnosed with HIV in Colombia were included.
Nathaly Ramírez-García
doaj +1 more source
Time‐to‐event prediction using survival analysis methods for Alzheimer's disease progression
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2021 Introduction Many research studies have well investigated Alzheimer's disease (AD) detection and progression. However, the continuous‐time survival prediction of AD is not yet fully explored to support medical practitioners with predictive analytics.
Rahul Sharma +3 more
doaj +1 more source
Frontiers in Physiology, 2022 Background: Real-world data on the impact of sex on the disease progression and prognosis of Crohn’s disease (CD) from large-scale Chinese cohorts are lacking.Aims: This study aimed to evaluate sex disparities in the clinical characteristics of, disease ...
Zhaoshi Liu +5 more
doaj +1 more source
Survival trees for left-truncated and right-censored data, with application to time-varying covariate data [PDF]
, 2016 Tree methods (recursive partitioning) are a popular class of nonparametric methods for analyzing data. One extension of the basic tree methodology is the survival tree, which applies recursive partitioning to censored survival data. There are several existing survival tree methods in the literature, which are mainly designed for right-censored data. We
arxiv +1 more source