Results 71 to 80 of about 25,673,599 (348)
Time‐to‐event prediction using survival analysis methods for Alzheimer's disease progression
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2021 Introduction Many research studies have well investigated Alzheimer's disease (AD) detection and progression. However, the continuous‐time survival prediction of AD is not yet fully explored to support medical practitioners with predictive analytics.
Rahul Sharma +3 more
doaj +1 more source
Frontiers in Physiology, 2022 Background: Real-world data on the impact of sex on the disease progression and prognosis of Crohn’s disease (CD) from large-scale Chinese cohorts are lacking.Aims: This study aimed to evaluate sex disparities in the clinical characteristics of, disease ...
Zhaoshi Liu +5 more
doaj +1 more source
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Cogent Medicine, 2021 : Breast cancer is the major public health problem throughout the world and it results in serious physical damages and death. This work proposes the use of joint model to study breast cancer in patients of Ayder Hospital.
Bsrat Tesfay +2 more
doaj +1 more source
eLife, 2021 Background: Sanofi-Pasteur’s CYD-TDV is the only licensed dengue vaccine. Two phase three trials showed higher efficacy in seropositive than seronegative recipients.
Daniel J Laydon +5 more
doaj +1 more source
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
icenReg: Regression Models for Interval Censored Data in R
Journal of Statistical Software, 2017 The non-parametric maximum likelihood estimator and semi-parametric regression models are fundamental estimators for interval censored data, along with standard fullyparametric regression models.
Clifford Anderson-Bergman
doaj +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
Culling Rate of Icelandic Horses due to Bone Spavin
Acta Veterinaria Scandinavica, 2003 A survival analysis was used to compare the culling rate of Icelandic horses due to the presence of radiographic and clinical signs of bone spavin. A follow-up study of 508 horses from a survey five years earlier was performed. In the original survey 46%
Árnason Th, Lord P, Björnsdóttir S
doaj +1 more source
Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source