Results 91 to 100 of about 4,691,817 (292)

JM: An R Package for the Joint Modelling of Longitudinal and Time-to-Event Data

Journal of Statistical Software, 2010
In longitudinal studies measurements are often collected on different types of outcomes for each subject. These may include several longitudinally measured responses (such as blood values relevant to the medical condition under study) and the time at ...
Dimitris Rizopoulos
doaj  

Magnitude and determinants of adherence to iron-folic acid supplementation among Somaliland pregnant women in Ahmed-dhagah district: A facility based cross-sectional study

Clinical Epidemiology and Global Health
Background: Iron deficiency is a major cause of anemia globally, especially in low-income countries, and pregnant women are at higher risk. Despite guidelines recommending IFA supplementation, adherence remains low. Therefore, the aim of this study is to
Ahmed Ismail Mohamed, Jama Mohamed, Mohamed Mussa Abdillahi, Barkhad Aden Abdeeq, Tefera Belachew Lema   +4 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Modeling Discrete Survival Time Using Genomic Feature Data

Cancer Informatics, 2015
Researchers have recently shown that penalized models perform well when applied to high-throughput genomic data. Previous researchers introduced the generalized monotone incremental forward stagewise (GMIFS) method for fitting overparameterized logistic ...
Kyle Ferber, Kellie J. Archer
doaj   +2 more sources

Machine learning to evaluate the effects of non-clinical social determinant features in predicting colorectal Cancer mortality in a medically underserved Appalachian population

Scientific Reports
Colorectal cancer (CRC) is the 2nd leading cause of cancer death in the United States (US). Rural Appalachia suffers the highest CRC incidence and mortality rates. There are several non-clinical health-related social determinant factors (SDOH) associated
Aisha Montgomery, Ravi Vadapalli, Frank A. Dinenno, Josh Schilling, Praduman Jain, Aasems Jacob, David Chism, Anil Shanker   +7 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

The University of Pittsburgh: a three and three-quarter-year experience with cadaveric renal transplantation under the point system. [PDF]

, 1989
Eight hundred and sixty kidney transplants were performed at the University of Pittsburgh over a 3.75-year period between January 1, 1986 and October 19, 1989.
Fung, JJ, Hakala, TR, Hickey, D, Iwaki, Y, Jordan, ML, Shapiro, R, Starzl, TE, Tzakis, AG   +7 more
core  

Quantile Association for Bivariate Survival Data

Biometrics, 2016
SummaryBivariate survival data arise frequently in familial association studies of chronic disease onset, as well as in clinical trials and observational studies with multiple time to event endpoints. The association between two event times is often scientifically important.
Li, Ruosha, Cheng, Yu, Chen, Qingxia, Fine, Jason   +3 more
openaire   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Individual patient data meta-analysis of survival data using Poisson regression models

BMC Medical Research Methodology, 2012
Background An Individual Patient Data (IPD) meta-analysis is often considered the gold-standard for synthesising survival data from clinical trials. An IPD meta-analysis can be achieved by either a two-stage or a one-stage approach, depending on whether ...
Crowther Michael J, Riley Richard D, Staessen Jan A, Wang Jiguang, Gueyffier Francois, Lambert Paul C   +5 more
doaj   +1 more source