Results 101 to 110 of about 1,812,936 (307)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Market concentration, market dynamism and business survival [PDF]
, 2006 The paper uses a unique dataset comprising the population of new ventures that enter the UK market in 1998. We argue that we would expect the effect of market concentration on firm survival to be different according to whether an industry is static ...
Gorg, Holger +2 more
core
Engineering ReportsStandard distributions must be improved to enhance their capacity for data modeling because they do not inherently suit all sorts of data sets in an acceptable manner.
Tabassum Naz Sindhu +4 more
doaj +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
A Matter of Life and Death: Innovation and Firm Survival [PDF]
This paper examines the effects of innovation on the survival of manufacturing firms in the Netherlands. The demographics of firms according to their innovative performance and type of innovation are traced by using the Business Register population of ...
Elena Cefis, Orietta Marsili
core
Using weibull mixture distributions to model heterogeneous survival data [PDF]
, 2003 In this article we use Bayesian methods to fit a Weibull mixture model with an unknown number of components to possibly right censored survival data. This is done using the recently developed, birth-death MCMC algorithm.
Marín Díazaraque, Juan Miguel +5 more
core
Optimal designs for full and partial likelihood information - with application to survival models [PDF]
, 2015 Time-to-event data are often modelled through Cox's proportional hazards model for which inference is based on the partial likelihood function. We derive a general expression for the asymptotic covariance matrix of Cox's partial likelihood estimator for ...
Konstantinou, Maria +3 more
core +1 more source
The Exponentiated Power Generalized Weibull: Properties and Applications
Anais da Academia Brasileira de CiênciasWe propose a new lifetime model called the exponentiated power generalized Weibull (EPGW) distribution, which is obtained from the exponentiated family applied to the power generalized Weibull (PGW) distribution.
FERNANDO A. PEÑA-RAMÍREZ +3 more
doaj +1 more source
Oligodendroglial impact on axonal function and survival – a hypothesis
Current Opinion in Neurology, 2008 Although multiple sclerosis is considered the prototype of a primary autoimmune disease in the central nervous system, there is emerging evidence that primary oligodendrocyte dysfunctions can suffice to trigger a secondary immune response in the nervous system.
Kassmann, C., Nave, K.
openaire +4 more sources