Results 111 to 120 of about 17,500,545 (334)
Dependent competing risks: Bounds for net survival functions with fixed crude survival functions
Environment International, 1978 Abstract Using the formulation of latent failure times, the problem of inference on survival time in the presence of competing risks is discussed. Even for the simplified problem where dose and other covariates are fixed, it is not well known that the distributions of the latent failure times are not identifiable from the usual competing risks data ...
openaire +1 more source
Survival as a Function of Life Expectancy [PDF]
It is well known that life expectancy can be expressed as an integral of the survival curve. The reverse - that the survival function can be expressed as an integral of life expectancy - is also true.force of mortality, life expectancy, life table ...
James W. Vaupel, Maxim Finkelstein
core
Stem Cells Translational Medicine, 2016 Mesenchymal stem cell (MSC)‐based therapies are under broad investigation for applications in tissue repair but suffer from poor cell persistence and engraftment upon transplantation.
Steve S. Ho +4 more
semanticscholar +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Survival and function after left ventricular aneurysmectomy
The Journal of Thoracic and Cardiovascular Surgery, 1975 Operative and late postoperative results in 55 patients undergoing resection of a discrete, saccular type left ventricular aneurysm are described. All patients had occlusive lesions of either the left anterior descending or left main coronary artery, and 72 per cent had significant multivessel disease. Preoperative factors that correlated significantly
M, Cooperman +3 more
openaire +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Cross-validation and Peeling Strategies for Survival Bump Hunting using Recursive Peeling Methods
, 2015 We introduce a framework to build a survival/risk bump hunting model with a censored time-to-event response. Our Survival Bump Hunting (SBH) method is based on a recursive peeling procedure that uses a specific survival peeling criterion derived from non/
Choe, Michael +3 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
New Lifetime Alpha Power Exponential Weibull Distribution: Structure and Properties
Ibn Al-Haitham Journal for Pure and Applied SciencesIn statistics theory, adding a new parameter is considered one of the important things that help in producing statistical distributions more flexible and appropriate in data analysis.
Hiba Mahdi Saleh +2 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source