Results 121 to 130 of about 204,647,773 (266)

History of the Ohio Bureau of Motor Vehicles

, 2001
Title from caption (viewed Mar.
Ohio. Bureau of Motor Vehicles.
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Association among biomarkers, phenotypes, and motor milestones in Chinese patients with 5q spinal muscular atrophy types 1–3

Frontiers in Neurology
BackgroundBiomarkers can be used to assess the severity of spinal muscular atrophy (5q SMA; SMA). Despite their potential, the relationship between biomarkers and clinical outcomes in SMA remains underexplored.
Shijia Ouyang, Xiaoyin Peng, Wenchen Huang, Jinli Bai, Hong Wang, Yuwei Jin, Hui Jiao, Maoti Wei, Xiushan Ge, Fang Song, Yujin Qu   +10 more
doaj   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

The Survival of Motor Neuron Protein Acts as a Molecular Chaperone for mRNP Assembly

, 2017
Spinal muscular atrophy (SMA) is a motor neuron disease caused by reduced levels of the survival of motor neuron (SMN) protein. SMN is part of a multiprotein complex that facilitates the assembly of spliceosomal small nuclear ribonucleoproteins (snRNPs).
Paul G. Donlin-Asp, Megan E. Merritt, Claudia Fallini, Han C. Phan, Ching-Chieh Chou, Wilfried Rossoll, Gary J. Bassell, Jazmin Campos   +7 more
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Human iPSC‐Derived Tissue‐Engineered Nigrostriatal Pathway for Chronic Restoration of Dopaminergic Axon Tracts in a Rat Parkinson's Model

Advanced Healthcare Materials, EarlyView.
Inspired by conventional cell therapy and emerging bioengineering approaches, the tissue‐engineered nigrostriatal pathway (TE‐NSP) has an anatomically‐inspired design comprising a population of human dopaminergic neurons with unidirectional, long‐projecting axon tracts.
Wisberty J. Gordián‐Vélez, Dimple Chouhan, Kevin D. Browne, James Lim, Saarang P. Karandikar, Rodrigo A. España, John E. Duda, H. Isaac Chen, D. Kacy Cullen   +8 more
wiley   +1 more source

The COPI vesicle complex binds and moves with survival motor neuron within axons

, 2011
Spinal muscular atrophy (SMA), an inherited disease of motor neuron dysfunction, results from insufficient levels of the survival motor neuron (SMN) protein.
Adrianne Kolpak, Jayakumar, Cyril P., Naoko Taniguchi-Ishigaki, Evans, Matthew C., Elliot J. Androphy, Thayanithy, Venugopal, Kolpak, Adrianne L., Wilfried, Rossoll, Cyril Jayakumar Peter, Gary J. Bassell, Bach, Ingolf, Christian L. Lorson, Androphy, Elliot J., Matthew Evans, Lorson, Christian L., Venugopal Thayanithy, Wilfried Rossoll, Bassell, Gary J., Taniguchi-Ishigaki, Naoko, Zheng-Zheng Bao, Bao, Zheng-Zheng, Ingolf Bach   +21 more
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GDNF‐Enriched Small Extracellular Vesicle‐Loaded ROS‐Scavenging Hydrogel Promotes Neural Regeneration After Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
A glial cell line‐derived neurotrophic factor (GDNF)‐enriched small extracellular vesicle‐loaded reactive oxygen species (ROS)‐scavenging hydrogel integrates sustained neurotrophic delivery with local modulation of oxidative and inflammatory stress after spinal cord injury. The composite hydrogel improves local vesicle retention, protects neural tissue,
Xingyu Zhu, Zhong Liu, Kewei Li, Yuhong Fan, Kangjia Yang, Xiaopeng Sun, Hang Shi, Lixuan Sun, Yang Lou, Min Wang, Peipei Wu, Hui Qian, Qiang Fu, Hua Ding   +13 more
wiley   +1 more source

Study of Protein Production, Folding, Crystallization and Structure: Survival of Motor Neuron Protein and Fenna-Matthews-Olson Protein [PDF]

, 2010
: Protein crystallization has become an extremely important tool in biochemistry since the first structure of the protein Myoglobin was solved in 1958. Survival of motor neuron protein has proved to be an elusive target in regards to producing crystals ...

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Microfluidic Engineering of Microgels: A Review of Emerging Technologies, Materials, Fabrication Strategies, and Applications

Advanced Healthcare Materials, EarlyView.
Recent advances in microfluidic technologies for microgel fabrication are critically reviewed, highlighting the capabilities and limitations of major microfluidic platforms and discussing how platform design, material selection, and crosslinking strategies influence microgel architecture and functionality. Current challenges and future opportunities in
Afshin Abrishamkar, Laura Neely, Cynthia Pham, Nada Ibrahim, Alexis Larios‐Cervantes, Ben A. Kertesz, Todd Hoare   +6 more
wiley   +1 more source

Clinical neurophysiology of motor neuron diseases /

, 2004
Includes bibliographical references and index.Print version record.Foreword. List of Contributors. 1. Overview (A. Eisen).I. Anatomy and Physiology of the Human Motor System. 2. Comparative anatomy of the motor system: differences in the organization of
Eisen, Andrew
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