Results 111 to 120 of about 2,840,578 (328)

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Transcriptional Alterations of Virulence-Associated Genes in Extended Spectrum Beta-Lactamase (ESBL)-Producing Uropathogenic Escherichia coli during Morphologic Transitions Induced by Ineffective Antibiotics

open access: yesFrontiers in Microbiology, 2017
It is known that an ineffective antibiotic treatment can induce morphological shifts in uropathogenic Escherichia coli (UPEC) but the virulence properties during these shifts remain to be studied.
Isak Demirel   +8 more
doaj   +1 more source

Valley susceptibility of an interacting two-dimensional electron system

open access: yes, 2006
We report direct measurements of the valley susceptibility, the change of valley population in response to applied symmetry-breaking strain, in an AlAs two-dimensional electron system.
De Poortere, E. P.   +5 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

LIN28B Polymorphisms Influence Susceptibility to Epithelial Ovarian Cancer [PDF]

open access: bronze, 2011
Jennifer Permuth‐Wey   +44 more
openalex   +1 more source

Post-harvest disease : Effects of the physiological age of bananas on their susceptibility to wound anthracnose caused by Colletotrichum musae [PDF]

open access: yes, 2008
Wound anthracnose caused by Colletotrichum e, and early ripening are the main problems affecting the quality of export bananas from a lot of countries in the world. In the case of Guadeloupe in French West Indies, these problems generally concern bananas
Chillet, Marc   +2 more
core  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

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