Results 31 to 40 of about 1,629,436 (316)
Systematic Approximations to Susceptible-Infectious-Susceptible Dynamics on Networks [PDF]
PLOS Computational Biology, 2016 Network-based infectious disease models have been highly effective in elucidating the role of contact structure in the spread of infection. As such, pair- and neighbourhood-based approximation models have played a key role in linking findings from network simulations to standard (random-mixing) results.
Matt J. Keeling +3 more
openaire +5 more sources
Introduction to Quantitative Susceptibility Mapping and Susceptibility Weighted Imaging [PDF]
The British Journal of Radiology, 2019 Quantitative Susceptibility Mapping (QSM) and Susceptibility Weighted Imaging (SWI) are MRI techniques that measure and display differences in the magnetization that is induced in tissues, i.e. their magnetic susceptibility, when placed in the strong external magnetic field of an MRI system. SWI produces images in which the contrast is heavily weighted
Pascal P. R. Ruetten +2 more
openaire +2 more sources
The genetics of infectious disease susceptibility: has the evidence for epistasis been overestimated? [PDF]
, 2013 Interactions amongst genes, known as epistasis, are assumed to make a substantial contribution to the genetic variation in infectious disease susceptibility, but this claim is controversial.
Ebert, Dieter +4 more
core +1 more source
Minigene Splicing Assays Identify 12 Spliceogenic Variants of BRCA2 Exons 14 and 15
Frontiers in Genetics, 2019 A relevant fraction of BRCA2 variants is associated with splicing alterations and with an increased risk of hereditary breast and ovarian cancer (HBOC). In this work, we have carried out a thorough study of variants from BRCA2 exons 14 and 15 reported at
Eugenia Fraile-Bethencourt +5 more
doaj +1 more source
Nature Communications, 2023 Radiation colitis is the leading cause of diarrhea and hematochezia in pelvic radiotherapy patients. This work advances the pathogenesis of radiation colitis from the perspective of ferroptosis.
Yue Feng +6 more
doaj +1 more source
Personal susceptibility to pitch [PDF]
Occupational and Environmental Medicine, 1970 Hodgson, G. A., and Whiteley, H. J. (1970).Brit. J. industr. Med.,27, 160-166. Personal susceptibility to pitch. During the years 1957 to 1963, 59 cases of hyperplastic squamous lesions were referred to us from a local patent fuel works where ovoids were made by fusing coal dust and pitch together by steam heat.
G A, Hodgson, H J, Whiteley
openaire +2 more sources
Identification of Eight Spliceogenic Variants in BRCA2 Exon 16 by Minigene Assays
Frontiers in Genetics, 2018 Genetic testing of BRCA1 and BRCA2 identifies a large number of variants of uncertain clinical significance whose functional and clinical interpretations pose a challenge for genetic counseling.
Eugenia Fraile-Bethencourt +5 more
doaj +1 more source
Scientific Reports, 2023 Genome-wide association studies have identified thousands of loci associated with common diseases and traits. However, a large fraction of heritability remains unexplained.
Anna Díez-Villanueva +9 more
doaj +1 more source
Frontiers in Genetics, 2020 A large fraction of DNA variants impairs pre-mRNA splicing in human hereditary disorders. Crigler-Najjar syndrome (CNS) is characterized by a severe unconjugated hyperbilirubinemia caused by variants in the UGT1A1 gene.
Linda Gailite +5 more
doaj +1 more source