Results 21 to 30 of about 2,659,607 (293)
Neisseria meningitidis-Induced Caspase-1 Activation in Human Innate Immune Cells Is LOS-Dependent
Journal of Immunology Research, 2019 Meningococcal disease such as sepsis and meningitidis is hallmarked by an excessive inflammatory response. The causative agent, Neisseria meningitidis, expresses the endotoxin lipooligosaccharide (LOS) that is responsible for activation of immune cells ...
Berhane Asfaw Idosa +6 more
doaj +1 more source
Loss of RASGRP1 in humans impairs T‐cell expansion leading to Epstein‐Barr virus susceptibility
EMBO Molecular Medicine, 2018 Inherited CTPS1, CD27, and CD70 deficiencies in humans have revealed key factors of T‐lymphocyte expansion, a critical prerequisite for an efficient immunity to Epstein–Barr virus (EBV) infection.
Sarah Winter +9 more
doaj +1 more source
Antifungal Resistance Analysis of Environmental Isolates of Aspergillus in North India
Journal of Pure and Applied Microbiology, 2019 Triazoles are the major group of antifungals for treating Aspergillus infections. The morbidity and mortality associated with these infections is high and rate of treatment failure is more in patients infected with azole resistant Aspergillus.
Shanu Hoda +4 more
doaj +1 more source
Revealing new tick-borne encephalitis virus foci by screening antibodies in sheep milk
Parasites & Vectors, 2020 Background Tick distribution in Sweden has increased in recent years, with the prevalence of ticks predicted to spread towards the northern parts of the country, thus increasing the risk of tick-borne zoonoses in new regions. Tick-borne encephalitis (TBE)
Amélie Wallenhammar +8 more
doaj +1 more source
Journal of Pure and Applied Microbiology, 2019 Clinical limitations and drug-resistance are the basis of the search for new antifungal therapeutics against biofilm forming pathogen Aspergillus fumigatus.
Shanu Hoda +5 more
doaj +1 more source
Minigene Splicing Assays Identify 12 Spliceogenic Variants of BRCA2 Exons 14 and 15
Frontiers in Genetics, 2019 A relevant fraction of BRCA2 variants is associated with splicing alterations and with an increased risk of hereditary breast and ovarian cancer (HBOC). In this work, we have carried out a thorough study of variants from BRCA2 exons 14 and 15 reported at
Eugenia Fraile-Bethencourt +5 more
doaj +1 more source
Nature Communications, 2023 Radiation colitis is the leading cause of diarrhea and hematochezia in pelvic radiotherapy patients. This work advances the pathogenesis of radiation colitis from the perspective of ferroptosis.
Yue Feng +6 more
doaj +1 more source
Reduced fidelity in Kitaev honeycomb model
, 2010 We study the reduced fidelity and reduced fidelity susceptibility in the Kitaev honeycomb model. It is shown that the reduced fidelity susceptibility of two nearest site manifest itself a peak at the quantum phase transition point, although the one-site ...
Gu, Shi-Jian +3 more
core +1 more source
Identification of Eight Spliceogenic Variants in BRCA2 Exon 16 by Minigene Assays
Frontiers in Genetics, 2018 Genetic testing of BRCA1 and BRCA2 identifies a large number of variants of uncertain clinical significance whose functional and clinical interpretations pose a challenge for genetic counseling.
Eugenia Fraile-Bethencourt +5 more
doaj +1 more source
Scientific Reports, 2023 Genome-wide association studies have identified thousands of loci associated with common diseases and traits. However, a large fraction of heritability remains unexplained.
Anna Díez-Villanueva +9 more
doaj +1 more source