Results 71 to 80 of about 2,840,578 (328)

Activation of the NLRP3 Inflammasome Pathway by Uropathogenic Escherichia coli Is Virulence Factor-Dependent and Influences Colonization of Bladder Epithelial Cells

Frontiers in Cellular and Infection Microbiology, 2018
The NLRP3 inflammasome and IL-1β release have recently been suggested to be important for the progression of urinary tract infection (UTI). However, much is still unknown regarding the interaction of UPEC and the NLRP3 inflammasome.
Isak Demirel, Isak Demirel, Alexander Persson, Alexander Persson, Annelie Brauner, Eva Särndahl, Eva Särndahl, Robert Kruse, Robert Kruse, Robert Kruse, Katarina Persson, Katarina Persson   +11 more
doaj   +1 more source

On the spin susceptibility of noncentrosymmetric superconductors

, 2007
We calculate the spin susceptibility of a superconductor without inversion symmetry, both in the clean and disordered cases. The susceptibility has a large residual value at zero temperature, which is further enhanced in the presence of scalar impurities.
A. A. Abrikosov, A. A. Abrikosov, A. A. Abrikosov, E. I. Rashba, E. I. Rashba, J. P. Elliott, K. V. Samokhin, L. N. Bulaevskii, L. N. Bulaevskii, L. P. Gor’kov, L. P. Gor’kov, M. Yogi, V. M. Edelstein, V. M. Edelstein, V. P. Mineev   +14 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Inactivation of cytidine triphosphate synthase 1 prevents fatal auto-immunity in mice

Nature Communications
De novo synthesis of the pyrimidine, cytidine triphosphate (CTP), is crucial for DNA/RNA metabolism and depends on the CTP synthetases, CTPS1 and −2. Partial CTPS1 deficiency in humans has previously been shown to lead to immunodeficiency, with impaired ...
Claire Soudais, Romane Schaus, Camille Bachelet, Norbert Minet, Sara Mouasni, Cécile Garcin, Caique Lopes Souza, Pierre David, Clara Cousu, Hélène Asnagli, Andrew Parker, Paul Palmquist-Gomes, Fernando E. Sepulveda, Sébastien Storck, Sigolène M. Meilhac, Alain Fischer, Emmanuel Martin, Sylvain Latour   +17 more
doaj   +1 more source

Holographic fidelity susceptibility [PDF]

Physical Review D, 2017
For a field theory with a gravitational dual, we study holographic fidelity susceptibility for two states related by a deformation of a relevant operator. To do so, we study back reaction of a massive scalar field on the asymptotic behavior of the metric in an Einstein gravity coupled to a massive scalar field.
Alishahiha, Mohsen, Astaneh, Amin Faraji
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Identification of autophagy receptors for the Crohn’s disease-associated adherent-invasive Escherichia coli

Frontiers in Cellular and Infection Microbiology
IntroductionCrohn’s disease (CD) is a chronic inflammatory bowel disease, of which the etiology involves genetic, environmental and microbial factors.
Alison Da Silva, Guillaume Dalmasso, Anaïs Larabi, My Hanh Thi Hoang, My Hanh Thi Hoang, Elisabeth Billard, Nicolas Barnich, Hang Thi Thu Nguyen   +7 more
doaj   +1 more source

Macrophages Inability to Mediate Adherent-Invasive E. coli Replication is Linked to Autophagy in Crohn’s Disease Patients

Cells, 2019
The macrophages from Crohn’s Disease (CD) patients are defective to control the replication of CD-associated adherent-invasive E. coli (AIEC). We aimed to identify the host factors associated with AIEC replication focusing on polymorphisms related ...
Anthony Buisson, Clara Douadi, Lemlih Ouchchane, Marion Goutte, Jean-Pierre Hugot, Anaëlle Dubois, Régine Minet-Quinard, Damien Bouvier, Gilles Bommelaer, Emilie Vazeille, Nicolas Barnich   +10 more
doaj   +1 more source

Novel Magnetic and Thermodynamic Properties of Thiospinel Compound CuCrZrS$_{4}$ [PDF]

, 2005
We have carried out dc magnetic susceptibility, magnetization and specific heat measurements on thiospinel CuCrZrS$_{4}$. Below $T_{\rm C}^{*} =$ 58 K, dc magnetic susceptibility and magnetization data show ferromagnetic behavior with a small spontaneous
F. K. Lotgering, Hiroki Yamamoto, K. Obayashi, Masakazu Ito, N. H. Van Maaren, S. Nagata, Shoichi Nagata, T. Kanomata, Takashi Suzuki   +8 more
core   +3 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source