Results 91 to 100 of about 4,800,471 (257)

Assessment and feedback to students

, 2011
This is one of ten resource units developed and released by the CPD4HE project. The resources support the professional development of HE teachers. They are aimed particularly at staff working towards HEA accreditation but are available to anyone who may ...
Dr Rosalind Duhs
core  

Monitoring and Assessment of Slope Hazards Susceptibility Around Sarez Lake in the Pamir by Integrating Small Baseline Subset InSAR with an Improved SVM Algorithm

Remote Sensing
Sarez Lake, situated at one of the highest altitudes among naturally dammed lakes, is regarded as potentially hazardous due to its geological setting.
Yang Yu, Changming Zhu, Majid Gulayozov, Junli Li, Bingqian Chen, Qian Shen, Hao Zhou, Wen Xiao, Jafar Niyazov, Aminjon Gulakhmadov   +9 more
doaj   +1 more source

Assessing the Psychological Impact of Genetic Susceptibility Testing [PDF]

Hastings Center Report, 2019
AbstractThe expanded use of genetic testing raises key ethical and policy questions about possible benefits and harms for those receiving disease‐risk information. As predictive testing for Huntington’s was initiated in a clinical setting, survey research posing hypothetical test scenarios suggested that the vast majority of at‐risk relatives wanted to
openaire   +2 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

A Methodology for Susceptibility Assessment of Wave-Induced Seabed Liquefaction in Silt-Dominated Nearshore Environments

Journal of Marine Science and Engineering
Wave-induced seabed liquefaction significantly jeopardizes the stability of marine structures and the safety of human life. Susceptibility assessment is key to enabling spatial predictions and establishing a solid foundation for effective risk analysis ...
Yueying Wang, Xingsen Guo, Jinkun Liu, Fang Hou, Hong Zhang, Han Gao, Xiaolei Liu   +6 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Landslide Susceptibility Assessment in Yulong County Using Contribution Degree Clustering Method and Stacking Ensemble Coupled Model Based on Certainty Factor

Remote Sensing
To address the subjectivity of traditional factor attribute grading methods and the weak predictive capabilities of single-model classifications, this study focused on Yulong County; the Contribution Degree Clustering Method (CDCM) utilizes the Certainty
Yang Qin, Zhifang Zhao, Dingyi Zhou, Kangtai Chang, Qiaomu Mou, Yonglin Yang, Yunfei Hu   +6 more
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source