Functional Expression of Recombinant Candida auris Proteins in Saccharomyces cerevisiae Enables Azole Susceptibility Evaluation and Drug Discovery. [PDF]
J Fungi (Basel), 2023 Toepfer S +3 more
europepmc +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
SensorsLandslide susceptibility mapping (LSM) is widely used for identifying potential landslide-prone areas. However, many existing approaches rely on global models that assume spatial stationarity, which limits their ability to capture spatially heterogeneous
Weiheng Qian +4 more
doaj +1 more source
Machine-learning-based ground sink susceptibility evaluation using underground pipeline data in Korean urban area. [PDF]
Sci Rep, 2022 Park JH, Kang J, Kang J, Mun D.
europepmc +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Molecular Detection of Clumping factor A gene and Antibiotic Susceptibility Evaluation of Staphylococcus Aureus Isolated from Urinary Tract Infections. [PDF]
Arch Razi Inst, 2022 Maki N Al-Muaala A +3 more
europepmc +1 more source
Report of the IEA Workshop on Evaluating the Quality of Science, Rome, 10-11 December 2015
, 2020 IEA organized a 1.5 day (10-11 December 2015) internal workshop to discuss approaches and experiences in assessing science quality, primarily through evaluations in the CGIAR.
CGIAR Independent Evaluation Arrangement
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Quantitative landslide susceptibility assessment of the Waikato region using GIS [PDF]
, 2010 Areas that have experienced landslide events in the past and the conditioning factors present at these sites can be used to identify areas of the same or similar susceptibility.
Schicker, Renee Deborah
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Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Evaluation of genetic tests for susceptibility to common complex diseases: why, when and how?
, 2010 Recent research into the human genome has generated a wealth of scientific knowledge and increased both public and professional interest in the concept of personalised medicine.
Kroese, Mark, Wright, Caroline Fiona
core +1 more source