Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
ANTIMICROBIAL RESISTANCE OF BACTERIAL AGENTS OF THE UPPER RESPIRATORY TRACT IN SOUTH INDIAN POPULATION [PDF]
The study was aimed at determining bacterial agents of the upper respiratory tract and the susceptibility patterns of isolates to antibiotics. The throat swab samples from 250 patients suspected of upper respiratory tract infection (URTI) were obtained ...
K. Kousalya +5 more
doaj
Efecto fitotóxico de imidazolinonas sobre trigo susceptible e imi-tolerante durante implantación [PDF]
Debido a su acción residual, la persistencia de imidazolinonas puede provocar fitotoxicidad en cultivos sembrados posteriormente a materiales imi-tolerantes.
Yanniccari, Marcos Ezequiel +4 more
core
TGF-b2 induction regulates invasiveness of theileria-transformed leukocytes and disease susceptibility [PDF]
Theileria parasites invade and transform bovine leukocytes causing either East Coast fever (T. parva), or tropical theileriosis (T. annulata). Susceptible animals usually die within weeks of infection, but indigenous infected cattle show markedly reduced
Regina Lizundia +69 more
core +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Carbapenem-resistant and cephalosporin-susceptible Pseudomonas aeruginosa: a notable phenotype in patients with bacteremia [PDF]
Shuang Li,1,* Xiaojiong Jia,1,* Congya Li,1 Hua Zou,1 Hang Liu,1 Yuanbiao Guo,2 Liping Zhang1 1Department of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China; 2Medical Research Center, The Second ...
Zou H +6 more
core
Chagas disease control in Venezuela: lessons for the Andean region and beyond. [PDF]
Following the success of the Southern Cone programme to control Chagas disease, Andean countries are beginning to implement a similar international initiative.
Feliciangeli, Maria Dora +5 more
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Uma das prioridades do Programa de Melhoramento Genético de Macieira da Epagri é a obtenção de cultivares resistentes à mancha foliar de glomerella - MFG, doença essa causada principalmente pela espécie Colletotrichum gloeosporioides, que tem causado ...
Carla Regina Costa Furlan +4 more
doaj +1 more source
Pefloxacin therapy for experimental endocarditis caused by methicillin-susceptible or methicillin-resistant strains of Staphylococcus aureus [PDF]
The therapeutic efficacy of pefloxacin in experimental endocarditis caused by methicillin-susceptible or methicillin-resistant Staphylococcus aureus was evaluated.
Täuber, MG +5 more
core +1 more source

