Results 71 to 80 of about 180,384 (297)

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

Target Analysis and Suspect Screening of Per- and Polyfluoroalkyl Substances in Tap Water Samples throughout Chinese Cities

Proceedings
1 [...]
Tieqing You, Jia Bao
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Correlation between radial peripapillary vascular density and reduced central corneal thickness in glaucoma suspect patients

BMC Ophthalmology, 2022
Background Optical coherence tomography (OCT) angiography (OCTA) provides a quantitative assessment of the microcirculation of the retina and choroid. It may precede the retinal nerve layer (RNFL) and optic disc head defects.
Ayman Lotfy, Hala Kamal Mattout, Sameh Mosaad Fouda, Sahar Hemeda   +3 more
doaj   +1 more source

Laboratory Focus on Improving the Culture of Biosafety: Statewide Risk Assessment of Clinical Laboratories That Process Specimens for Microbiologic Analysis [PDF]

, 2018
The Wisconsin State Laboratory of Hygiene challenged Wisconsin laboratories to examine their biosafety practices and improve their culture of biosafety.
Batemman, Allen C., Beck, eric, Block, Timothy K., Bowles, Erin J., Dern, Richard, Kropp, Joshua L., Munson, Erik, Podzorski, Raymond P., Radke, Tyler, Siebers, Karen, Simmons, Brian, Smith, Mary A., Spray-Larson, Frances, Warshauer, David M.   +13 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Linking high resolution mass spectrometry data with exposure and toxicity forecasts to advance high-throughput environmental monitoring

Environment International, 2016
There is a growing need in the field of exposure science for monitoring methods that rapidly screen environmental media for suspect contaminants. Measurement and analysis platforms, based on high resolution mass spectrometry (HRMS), now exist to meet ...
Julia E. Rager, Mark J. Strynar, Shuang Liang, Rebecca L. McMahen, Ann M. Richard, Christopher M. Grulke, John F. Wambaugh, Kristin K. Isaacs, Richard Judson, Antony J. Williams, Jon R. Sobus   +10 more
doaj   +1 more source

Descriptive Analysis of Sexual Assault Nurse Examinations in Bethel: 2005-2006 [PDF]

, 2007
This project examined the characteristics of 105 sexual assault victimizations recorded by sexual assault nurse examiners in Bethel, Alaska in 2005 and 2006.
Henry, Tara, Rosay, André B., The Alaska Department of Law, Yukon-Kuskokwim Health Corporation   +3 more
core  

Updated estimate of the duration of the meningo-encephalitic stage in gambiense human African trypanosomiasis [PDF]

, 2015
Background: The duration of the stages of HAT is an important factor in epidemiological studies and intervention planning. Previously, we published estimates of the duration of the haemo-lymphatic stage 1 and meningo-encephalitic stage 2 of the ...
Chandramohan, Daniel, Chappuis, François, Checchi, Francesco, Funk, Sebastian, Haydon, Daniel T.   +4 more
core   +2 more sources