Results 221 to 230 of about 923,709 (288)

MAM‐Localized MANF Counteracts Microinflammatory Stress to Attenuate Mitochondrial Dysfunction and Cataractogenesis in High Myopia

Advanced Science, EarlyView.
Chronic microinflammation in high myopia suppresses MANF in lens epithelial cells. MANF normally resides within MAMs and promotes ubiquitin‐mediated degradation of the ER Ca2+ pump SERCA2. MANF loss causes pathological SERCA2 accumulation, MAM hyperassembly, and disrupted ER‐to‐mitochondria Ca2+ transfer, leading to mitochondrial failure, oxidative ...
Xin Liu, Hao Li, Ching Kang, Dongling Guo, Shuyu Liu, Jiaqi Meng, Zhiqian Huang, Yu Du, Xiangjia Zhu   +8 more
wiley   +1 more source

Evaluation of the Collection Efficiency of a Wet-Type Electrostatic Precipitator for Aerosolized Influenza A Virus. [PDF]

Microorganisms
Nakamura K, Nagai T, Ishiguro H, Kobayashi K, Nakagawa K, Okanojo M, Nukazuka A.   +6 more
europepmc   +1 more source

High Tree Species Diversity Promotes Thermal Enhancement Response of Microbial Carbon Use Efficiency

Advanced Science, EarlyView.
ABSTRACT Predicting soil carbon dynamics under warming is constrained by limited understanding of microbial thermal adaptation, particularly whether microbial carbon use efficiency (CUE) can adapt to warming and how plant diversity modulates this response. Using soils from a natural tree species diversity gradient in a subtropical forest, we combined a
Pengpeng Duan, Changqing Ye, Xinyi Yang, Chaoqun Wang, Wolfgang Wanek, Jian‐sheng Ye, Hongzhao Yuan, Hu Du, Kongcao Xiao, Xunyang He, Kelin Wang, Dejun Li   +11 more
wiley   +1 more source

WHO's 2026 emergency appeal and global health security. [PDF]

Global Health
Abdi YH, Bashir SG, Osman WA, Abdulle AA.   +3 more
europepmc   +1 more source

Targeting the ATX‐LPA Axis Overcomes TKI Resistance and Immunosuppression in Renal Cell Carcinoma via Dual Inhibition of AKT/mTOR and TBK1/IRF3 Pathways

Advanced Science, EarlyView.
ABSTRACT Background Therapeutic resistance limits durable survival in advanced/metastatic renal cell carcinoma (RCC) treated with first‐line tyrosine kinase inhibitor (TKI) plus immune checkpoint inhibitor (ICI). We sought to define key resistance drivers and actionable targets.
Jinchen Luo, Hansen Lin, Haoqian Feng, Lei Tan, Xi Liu, Yong Huang, Junjie Cen, Jiajie Chen, Xinwei Zhou, Mingjie Lin, Wuyuan Liao, Zheyu Ai, Minyu Chen, Yinghan Wang, Wei Chen, Junhang Luo, Yanping Liang   +16 more
wiley   +1 more source

Simulation of the additional damping characteristics of underwater heave plates for mitigating long-span bridges vibration. [PDF]

Sci Rep
An W, Xu F, Wang M.
europepmc   +1 more source

Mechanical properties analysis of the interspersed replacement of timber sleepers with bamboo-based composite sleepers on open bridge deck. [PDF]

Sci Rep
Chen P, Liu T, Xu W, Huang J, Li C.
europepmc   +1 more source

Cost-effective reconstruction of long-standing lateral orbital rim defect with bone-prelaminated forehead flap using iliac crest: A case report. [PDF]

Medicine (Baltimore)
Al-Marrawi A, Hammadeh H, Aldakak MA, Alhilbawi MH.   +3 more
europepmc   +1 more source

Parameter calibration of finite element model of reinforced concrete arch bridge based on ISOA-RBF neural network. [PDF]

Sci Rep
Peng W, Zhang Z, Tian Z, Zhang J, Zeng G.   +4 more
europepmc   +1 more source

Investigation of Wind Field Characteristics in Mountain Valley Terrain Under the Disturbance of Bridge Structures. [PDF]

Sensors (Basel)
Wu C, Zhang J, Yang H, Liu H, Ma R.
europepmc   +1 more source