Results 91 to 100 of about 414,542 (317)
Commentarii Mathematici Helvetici, 1968 The present paper is devoted to a study of the following process: take an ~ rbitrary map d: A-~X, use it to attach the cone CA to X and obtain a space B = X u CA, and then lift d in a natural way to a map e: A ~ F , where F is the "fibre" of the inclusion map X-*B.
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Dead-end and crossflow microfiltration of yeast and bentonite suspensions: experimental and modelling studies incorporating the use of artificial neural networks [PDF]
, 2008 The applicability of artificial neural networks (ANNs) and semi-empirical modelling techniques for correlation and prediction of the filtration characteristics of microfiltration systems was assessed.
Ní Mhurchú, Jenny
core
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Force chains and networks: wet suspensions through dry granular eyes
, 2019 Recent advances in shear-thickening suspension rheology suggest a relation between (wet) suspension flow below jamming and (dry) granular physics. To probe this connection, we simulated the contact force networks in suspensions of non-Brownian spheres ...
Royer, John R +3 more
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Aggregation of concentrated colloidal silica dispersions in flow [PDF]
, 2007 Concentrated suspensions of nanoparticles subjected to transport or shear forces are commonly encountered in many processes such as precipitation, wet comminution or filtration. In these processes, particles are likely to undergo processes of aggregation
Frances, Christine +8 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
BMJ, 2004 The process is badly handled at present, and new guidance is welcome For any employee to be excluded from work is a devastating blow, whatever the circumstances. In the case of doctors the safety of patients may be a justifiable reason, but the process that leads to that decision is not straightforward and in many cases the individuals concerned ...
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Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Nanomaterials, 2019 The industrial exploitation of high value nanoparticles is in need of robust measurement methods to increase the control over product manufacturing and to implement quality assurance.
Alexander Schavkan +12 more
doaj +1 more source