Results 101 to 110 of about 717,303 (307)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Caracterización y preparación de ceniza volante para su uso como recubrimientos cerámicos sobre substratos metálicos

Boletín de la Sociedad Española de Cerámica y Vidrio, 2008
Fly ash samples were characterized by atomic absorption, plasma spectroscopy, DTA/TGA, SEM/EDS, XRD and laser diffraction in order to obtain fly ash coatings on stainless steel substrates by electrophoretic deposition.
Chávez, A., Vargas, G., Almanza, J. M.
doaj  

Charge Renormalization, Effective Interactions, and Thermodynamics of Deionized Colloidal Suspensions

, 2008
Thermodynamic properties of charge-stabilised colloidal suspensions depend sensitively on the effective charge of the macroions, which can be substantially lower than the bare charge in the case of strong counterion-macroion association.
A R Denton, Belloni L, Denton A R, Denton A R, Derjaguin B V, Deserno M, Diehl A, Evans D F, Grier D G, Hansen J-P, Israelachvili J, Levin Y, Levin Y, Linse P, Lu B Denton A R, Oosawa F, Schmitz K S, Soukoulis C M, van Roij R, Verwey E J W, Warren P B   +20 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Tribological behaviour of copper oxide nanoparticle suspension [PDF]

, 2008
This work presents and discusses the tribological behaviour of nanoparticle suspensions in a polyalphaolefin (PAO6). CuO nanoparticles were separately dispersed at 0.5, 1.0 and 2.0% wt. in PAO6 using an ultrasonic probe for 2 minutes.
Fernandez, J.E., Hernandez Battez, Antolin, Viesca Rodriguez, J.L.   +2 more
core  

Wall slip across the jamming transition of soft thermoresponsive particles

, 2015
Flows of suspensions are often affected by wall slip, that is the fluid velocity $v_{f}$ in the vicinity of a boundary differs from the wall velocity $v_{w}$ due to the presence of a lubrication layer. While the slip velocity $v_s=\vert v_{f}-v_{w}\vert$
Divoux, Thibaut, Lapeyre, Véronique, Manneville, Sébastien, Ravaine, Valérie   +3 more
core   +3 more sources

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Rheological Modeling of Polymer/Layered Silicate Nanocomposites

Applied Rheology, 2011
This work takes a phenomenological approach to modeling the rheology of polymer/clay nanocomposites in ẏ ≤ 1 s-1 based on experimental observations [10].
Nazockdast Ehssan, Nazockdast Hossein
doaj   +1 more source