Results 111 to 120 of about 720,195 (285)

Rollover Preventive Force Synthesis at Active Suspensions in a Vehicle Performing a Severe Maneuver with Wheels Lifted off

, 2013
Among the intelligent safety technologies for road vehicles, active suspensions controlled by embedded computing elements for preventing rollover have received a lot of attention.
Parida, Nigam Chandra, Raha, Soumyendu, Ramani, Anand   +2 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Out-of-school suspensions and parental involvement in children’s education [PDF]

Do parents alter their investment in their child’s human capital in response to changes in school inputs? If they do, then ignoring this effect will bias the estimates of school and parental inputs in educational production functions. This paper tries to
Maria E. Canon
core  

Topological character of hydrodynamic screening in suspensions of hard spheres: an example of universal phenomenon

, 2008
Although in the case of polymer solutions the existence of hydrodynamic screening is considered as established, use of the same methods for suspensions of hard spheres so far have failed to produce similar results. In this work we reconsider this problem.
Arkady L. Kholodenko, Arnold, Batchelor, Batchelor, Benn, Berdichevsky, Berdichevsky, Bicerano, Bogoliubov, Brady, Brenner, Brereton, Brownstein, Cho, Cho, Chorin, Cottingham, De Gennes, Dirac, Doi, Dubrovin, Dunne, Edwards, Einstein, Einstein, Ethan E. Ballard, Ferrari, Ferraro, Ferrell, Feynman, Feynman, Garcia de Andrade, Gaudin, Ginzburg, Gonzales-Gascon, Hawksley, Hooper, Hoover, Iida, Jackiw, Jost, Kholodenko, Kholodenko, Kholodenko, Kholodenko, Kholodenko, Kholodenko, Kholodenko, Kholodenko, Kholodenko, Kholodenko, Kleinert, Kondo, Kozlov, Landau, Landau, Landau, Leggett, Lifshitz, London, London, Lovesey, Lund, Meeker, Moffatt, Moffatt, Nambu, Phan, Phillies, Pismen, Polyakov, Rallison, Ramond, Rasetti, Richardson, Rogers, Roscoe, Russel, Schief, Segre, Selim, Stack, Suzuki, Tadros, Tanaka, t’Hooft, Van Kampen, Veselov, Witten, Zaghloul   +89 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Impact of single-particle compressibility on the fluid-solid phase transition for ionic microgel suspensions

, 2014
We study ionic microgel suspensions composed of swollen particles for various single-particle stiffnesses. We measure the osmotic pressure $\pi$ of these suspensions and show that it is dominated by the contribution of free ions in solution.
Fernandez-Nieves, A., Goldbart, Paul M., Lyon, L. A., Pelaez-Fernandez, M., Souslov, Anton   +4 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Hopper flows of dense suspensions: a 2D microfluidic model system

Flow
Flows of particles through bottlenecks are ubiquitous in nature and industry, involving both dry granular materials and suspensions. However, difficulties in precisely controlling particle properties in conventional set-ups hinder the full understanding ...
Lars Kool, Jules Tampier, Philippe Bourrianne, Anke Lindner   +3 more
doaj   +1 more source