Results 101 to 110 of about 2,796,465 (333)
Assessment of Sustainability Value and Dignified Well-Being in Inclusive Product Lifecycles [PDF]
Sustainability is a concept mainly assessed by the features of a product that are considered as specific metrics for sustainability in an engineering context. However, sustainability is a comprehensive process for improvement in sustainable development that can be structured with the influence of inclusivity of empowered people.
arxiv
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik+3 more
wiley +1 more source
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui+15 more
wiley +1 more source
A User Interface Study on Sustainable City Trip Recommendations [PDF]
The importance of promoting sustainable and environmentally responsible practices is becoming increasingly recognized in all domains, including tourism. The impact of tourism extends beyond its immediate stakeholders and affects passive participants such as the environment, local businesses, and residents.
arxiv
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei+7 more
wiley +1 more source
Hypoxia‐guided treatment planning for lung cancer with dose painting by numbers
Abstract Tumor hypoxia significantly impacts the efficacy of radiotherapy. Recent developments in the technique of dose painting by numbers (DPBN) promise to improve the tumor control probability (TCP) in conventional radiotherapy for hypoxic cancer.
Yazhou Li+6 more
wiley +1 more source
Declaração de ...
2010 International Conference on Climate Sustainability and Development in Semi-arid Regions
doaj
A multi-model study to inform the United States’ 2035 NDC
In 2025, countries are expected to submit a third round of nationally determined contributions (NDCs) that outline emission reduction goals for 2035.
Gokul Iyer+12 more
doaj +1 more source