Results 161 to 170 of about 3,545,676 (334)

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Leeds Edible Schools Sustainability Network [PDF]

, 2014
There is a growing interest in both urban agriculture and the issue of sustainability, as framed in terms of climate change, landscape, economic uncertainty and resource shortages, while issues around child health and wellbeing are increasingly causing ...
Bliss, T, Dickinson, IM
core  

A call for an integrated approach to improve efficiency, equity and sustainability in rare disease research in the United States

, 2022
Meghan C. Halley, Hadley Stevens Smith, Euan A. Ashley, Aaron J. Goldenberg, Holly K. Tabor   +4 more
openalex   +2 more sources

Sustainable Entrepreneurship in Rural E-Commerce: Identifying Entrepreneurs in Practitioners by Using Deep Neural Networks Approach [PDF]

, 2022
Guojie Xie, Lijuan Huang, Hou Bin, Chrysostomos Apostolidis, Yaohui Jiang, Guokai Li, Weiwei Cai   +6 more
openalex   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Mesenchymal stem cells for the sustained in vivo delivery of bioactive factors

, 2010
Todd E. Meyerrose, Scott D. Olson, Suzanne Pontow, Stefanos Kalomoiris, Yunjoon Jung, Geralyn Annett, Gerhard Bauer, Jan A. Nolta   +7 more
openalex   +2 more sources

Recent Applications of Smart Technologies for Monitoring the Sustainability of Forest Operations [PDF]

, 2023
Rachele Venanzi, Francesco Latterini, Vincenzo Civitarese, Rodolfo Picchio   +3 more
openalex   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Carbon farming, overestimated negative emissions and the limits to emissions trading in land-use governance: the EU carbon removal certification proposal

Environmental Sciences Europe
This article conducts a qualitative governance analysis of the European Commission’s 2022 proposal for a certification framework for carbon removals (CRCF). It highlights potential challenges and legal implications—with a specific focus on carbon farming.
Philipp Günther, Beatrice Garske, Katharine Heyl, Felix Ekardt   +3 more
doaj   +1 more source