Results 121 to 130 of about 25,118 (264)

Issues of Justice in Sustainability Transitions

open access: yes
This chapter focuses on issues of justice in sustainability transitions. Although there is an increasing focus in academia, policymaking and practice on the importance making sustainability transitions not only environmentally and economically sustainable, but also just and fair so that costs and benefits are shared equally, this chapter illustrates ...
Sara Heidenreich   +2 more
openaire   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Global gridded population datasets systematically underrepresent rural population

open access: yesNature Communications
Numerous initiatives towards sustainable development rely on global gridded population data. Such data have been calibrated primarily for urban environments, but their accuracy in the rural domain remains largely unexplored.
Josias Láng-Ritter   +2 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Behaviour and the individual in sustainability transitions

open access: yes
This chapter explores the critical role of individual behaviour in sustainability transitions, a field that has traditionally focused more on macro-meso-level processes. While systemic changes in technology and policy are essential, the actions of individuals and small groups significantly influence the adoption of sustainable practices and the shaping
Elisabeth Dütschke   +2 more
openaire   +2 more sources

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