Results 91 to 100 of about 1,458,706 (335)

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Alternative strategies to prevent and control endoparasite diseases in organic sheep and goat farming systems – a review of current scientific knowledge [PDF]

, 2006
Infestation with gastro-intestinal nematodes in small ruminants can cause server economic losses and endanger animal welfare. The development of organic farming systems, the increased public awareness for drug residues in agricultural products and the ...
Rahmann, Gerold, Seip, Hannah
core  

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Determinants of Receptivity Towards Entomophagy among Young Adults

Mercados y Negocios
This research focuses on understanding the factors influencing the acceptance of entomophagy in Morelia, Michoacán. The study involves a survey aimed at two distinct groups of young adults aged 18 to 29 (control and experimental), a demographic known for
Carlos Francisco Ortiz Paniagua, Miguel Ángel Bautista Hernández, Paulina Lerch López   +2 more
doaj   +1 more source

Socio-economic impacts of alternative GIN control practices. Project deliverable 11 (WP4) [PDF]

, 2018
This report is a deliverable (WP4) from the EU-funded PrOPara project. The PrOPara project aspires to i) assess existing knowledge from research, development and benchmarking studies on alternatives to parasite control on organic ruminant farms, ii ...
Moakes, Simon, Quiédeville, Sylvain
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Alternative proteins; A path to sustainable diets and environment

Current Research in Food Science
With a growing global population and the resulting pressure on natural resources, the supply of high-value protein has become increasingly limited. The rise of environmental and ethical concerns has led to the emergence of meat analogues as a credible ...
Shima Jafarzadeh, Zeinab Qazanfarzadeh, Mahsa Majzoobi, Samira Sheiband, Nazila Oladzadabbasabad, Yasaman Esmaeili, Colin J. Barrow, Wendy Timms   +7 more
doaj   +1 more source

TRAP CROP RADISH: A SUSTAINABLE ALTERNATIVE FOR NEMATICIDE IN SUGAR BEETS [PDF]

Chemical treatment of nematodes in sugar beets can be very costly ($190 per acre), and hazardous, representing significant environmental risks to air, water and human health.
Gray, Fred A., Held, Larry J., Jennings, James W., Koch, David W.   +3 more
core   +1 more source

Pavement recycling: an environmentally sustainable rehabilitation alternative [PDF]

, 2007
The preservation of environment by reducing the use of material and natural resources together with important economic savings have led pavement recycling to be a prime solution for pavement maintenance/rehabilitation.
Oliveira, Joel, Pereira, Paulo A. A., Silva, Hugo Manuel Ribeiro Dias da   +2 more
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source