Results 71 to 80 of about 1,478,432 (305)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
ProceedingsThis work examines the thermal stability testing results of Mg84Cu16 as a new phase change material for its potential use in latent thermal energy storage systems for 488 °C transition temperatures.
Yassine El Karim +3 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Sustainable Preferences and Damage Abatement:Value Judgments and Implications for Consumption Streams [PDF]
This paper examines the implications of adopting alternative value judgements when evaluating future consumption streams in the context of damage abatement. The paper focusses on a form of ‘sustainable preferences’ designed to avoid either a dictatorship
John Creedy, Ross Guest
core
Between food ethics, solidarity and the social construction of alternative markets. Exploring the dimensions of grassroots food movements in Spain [PDF]
, 2010 In recent years there has been growing attention for the emergence of alternative food networks, first as a possible strategy for farm households to counter deteriorating market conditions and respond to changing societal demands, and more recently as ...
Calle Collado, Ángel +5 more
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Development of sustainable material for hybrid wall system to improve indoor thermal performance [PDF]
, 2017 Thermal performance of building envelope has been of great importance in determining the indoor thermal environment mainly due to the impact of existing global warming issues.
Narendra raut, Ashwin
core
Sustainable Chemical Alternatives
VOYAGERThe ruthless human desire for growth and development is killing the humankind. Human activity is affecting all the four domains (lithosphere, hydrosphere, atmosphere and biosphere) of Earth. All the domains are polluted to such an extent that they are no longer self-healing.
openaire +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
BioResourcesCurrent carbon footprint tools for the pulp and paper industry focus on conventional wood fibers and overlook alternative biomass and soil organic carbon (SOC) sequestration.
Rhonald Ortega +8 more
doaj