Results 91 to 100 of about 1,478,432 (305)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Alternative proteins; A path to sustainable diets and environment

open access: yesCurrent Research in Food Science
With a growing global population and the resulting pressure on natural resources, the supply of high-value protein has become increasingly limited. The rise of environmental and ethical concerns has led to the emergence of meat analogues as a credible ...
Shima Jafarzadeh   +7 more
doaj   +1 more source

What Green Economy? Diverse agendas, their tensions and potential futures [PDF]

open access: yes, 2014
The 'green economy' has become a prominent global concept for debating desirable futures, while recasting or marginalising ‘sustainable development’.
Levidow, Les
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

TRAP CROP RADISH: A SUSTAINABLE ALTERNATIVE FOR NEMATICIDE IN SUGAR BEETS [PDF]

open access: yes
Chemical treatment of nematodes in sugar beets can be very costly ($190 per acre), and hazardous, representing significant environmental risks to air, water and human health.
Gray, Fred A.   +3 more
core   +1 more source

Rural tourism: A sustainable alternative

open access: yesApplied Energy, 2011
The aim of this article is to show and share the results of the research we made in order to improve the situation of sustainable interior rural tourism in Spain. We chose our region: Aragon and we studied the case. We had to consider the financial crisis in the hope that our results would contribute to minimize it.
Sanagustín, Mª Victoria   +2 more
openaire   +3 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

A COMPARISON OF SUSTAINABLE AND CONVENTIONAL FARMERS IN NORTH DAKOTA [PDF]

open access: yes
Interviews and mail-out/mail-back surveys were conducted in 1992 with 38 conventional and 41 sustainable North Dakota farmers. The results emphasize the differences and similarities of these two types of farmers.
Goreham, Gary A.   +3 more
core   +1 more source

Priming the pump: exploring the impact of smart water pumps on communities in South Africa and Malawi, where water acces is problematic [PDF]

open access: yes, 2014
Drawing in particular on recent empirical work in South Africa and Malawi, this paper considers the potential that ‘SALT technology’ (sustainable, alternative, low-cost telemetry) has to help realize the goal of sufficient water for everyone by ...
Cooper, Nathan John
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy