Results 81 to 90 of about 5,352,929 (277)

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Biosurfactant production by fungi as a sustainable alternative

Arquivos do Instituto Biológico, 2018
: A wide variety of bacteria is far more exploited than fungi as biosurfactants (BS) or bioemulsifiers (BE), using renewable sources. BS are considered to be environmentally safe and offer advantages over synthetic surfactants.
Artemisia Carla Santos da Silva, Patrícia Nunes dos Santos, Thayse Alves Lima e Silva, Rosileide Fontenele Silva Andrade, Galba Maria Campos-Takaki   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Datblygu cynaliadwy a grwpiau ffydd y DU : dwy ochr yr un geiniog? : arolwg o weithgareddau datblygu cynaliadwy cymunedau ffydd y DU a’r camau nesaf ar gyfer y dyfodol [PDF]

, 2012
Report of UK faith communities and their SD activities plus next steps for the future.Welsh language version of 'Sustainable development and UK faith groups : two sides of the same coin?
World Wildlife Fund UK, Sustainable Development Commission   +1 more
core   +2 more sources

Determinants of Receptivity Towards Entomophagy among Young Adults

Mercados y Negocios
This research focuses on understanding the factors influencing the acceptance of entomophagy in Morelia, Michoacán. The study involves a survey aimed at two distinct groups of young adults aged 18 to 29 (control and experimental), a demographic known for
Carlos Francisco Ortiz Paniagua, Miguel Ángel Bautista Hernández, Paulina Lerch López   +2 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Sistem Pendukung Keputusan dalam Implementasi RSPO (Roundtable on Sustainable Palm Oil) pada Petani Pola Swadaya di Kabupaten Paser

Jurnal Agro Industri Perkebunan
Implementing RSPO (Roundtable on Sustainable Palm Oil) standards is one way to address the challenges palm oil products face in competing in the global market.
Muhamad Yazid Bustomi, Pandhu Rochman Suosa Putra, Andi Lelanovita Sardianti, Zainal Abidin, Andi Lisnawati, Sukariyan Sukariyan   +5 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Sustainable communities policy review : Manchester/Salford [PDF]

, 2012
This report is part of the evidence base for 'In-depth review of sustainable communities policy'.This paper collates evidence from an Sustainable Development Commission visit, Audit Commission Manchester Salford Pathfinder reports (2003 & 2006) and ...
Sustainable Development Commission
core   +2 more sources

Bamboo as a sustainable alternative construction material: A review

Advances in Bamboo Science
Bamboo is one of the fastest-growing plants in the world, naturally abundant, and recognized as a highly sustainable and renewable material resource. Although the existing literature highlights its potential in the construction industry, bamboo's use ...
Wonder Salami Davor, Lucas Nana Wiredu Damoah, Benjamin Agyei-Tuffour   +2 more
doaj   +1 more source