Results 51 to 60 of about 543,127 (303)
The Sustainable Architectural Values of Eclectic Style Shophouses Case Study: Sun Yat Sen Museum Penang, Malaysia [PDF]
, 2017 The Sun Yat Sen shophouse in Penang is a small private Museum, which was converted from a shophouse or townhouse situated in theArmenian Street heritage area of George Town.
Bahauddin, A. (Azizi), Zwain, A. (Akram)
core +4 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Towards a new multilateral energy architecture? [PDF]
, 2012 From climate change over peak oil to the geopolitical scramble for the Arctic, there are ample signs that a global energy crisis is unfolding. The sheer scale and urgency of this looming crisis calls for international coordination.
Van de Graaf, Thijs
core +1 more source
Sustainable Earthen Architecture [PDF]
PhD Research Sympozium 2018, 2018 Sustainable architecture must meet environmental, sociocultural and economic criteria. Based on analysis and interpretation, this paper explores to what extent earthen building material meets these categories. Earth is a traditional, environmentally friendly, recyclable material that has a positive effect on human health.
openaire +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
BuildingsThermal comfort in public buildings is crucial for occupant well-being and energy efficiency. This study employs TRNSYS software to simulate the effects of thermal mass, window performance, and window–wall ratio (WWR) on summer thermal comfort.
Ran Cheng +5 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
The Architectural Sustainability Indicator
IEEE Computer Architecture LettersComputing devices are responsible for a significant fraction of the world's total carbon footprint. Designing sustainable systems is a challenging endeavor because of the huge design space, the complex objective function, and the inherent data uncertainty.
Jaime Roelandts +2 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source