Results 111 to 120 of about 482,645 (303)

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Green and Sustainable Chemistry in the Work of the United Nations Environment Programme: Results and Options for Future Regulation

Chemical Engineering Transactions
The expression of green and sustainable chemistry has gained significant attention around the world in recent years. Nowadays, it is evident that green and sustainable chemistry is necessary for Sustainable Development Goals (SDGs); however, the concept ...
Dalma Takó
doaj  

Synthesis of Diaryl‐ and Dialkynylphosphinates From Ubiquitous PV Sources via a Redox‐Neutral Approach

Advanced Science
Organophosphinic acids, R2P(O)(OH), and their derivatives are versatile compounds with applications in catalysis, material chemistry, biomolecular bridging, metal extraction, and flame retardancy.
Tobias Schneider, Kai Schwedtmann, Jannis Fidelius, Rosa M. Gomila, Antonio Frontera, Jan J. Weigand   +5 more
doaj   +1 more source

Toward sustainable solid-phase peptide synthesis strategy – in situ Fmoc removal

Green Chemistry Letters and Reviews
Solid-phase peptide synthesis (SPPS) is the method of choice for the synthesis of peptides for research and production purposes. Despite having several positive features, it remains a challenge to reduce the amount of solvent waste generated during the ...
Ndumiso Mthethwa, K. P. Nandhini, Ashish Kumar, Anamika Sharma, Beatriz G. de la Torre, Fernando Albericio   +5 more
doaj   +1 more source

AI4Green: An Open-Source ELN for Green and Sustainable Chemistry. [PDF]

J Chem Inf Model, 2023
Boobier S, Davies JC, Derbenev IN, Handley CM, Hirst JD.   +4 more
europepmc   +1 more source

Fifth International Conference on Renewable Resources and Biorefineries, 10-12 June 2009, Ghent, Belgium [PDF]

, 2009
B
Cukalovic, Ana
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Green and sustainable chemistry - The case for a systems-based, interdisciplinary approach. [PDF]

iScience, 2021
Constable DJC.
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

N‐Geranylated Amino Acid Surfactants with Low Critical Micelle Concentrations from Abundant, Naturally Derived Starting Materials

ChemistryOpen
In this work, a simple method for the preparation of N‐alkylated amino acid surfactants in 1–2 steps is reported. These products perform comparably to existing ionic surfactants, with N‐tetrahydrogeranylated serine having a critical micelle concentration
Brett L. Pollard, Yumeng Liu, Michael G. Gardiner, Luke A. Connal   +3 more
doaj   +1 more source