Results 91 to 100 of about 487,239 (300)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Química verde: a evolução de um conceito

open access: yesQuímica Nova, 2014
The topic "Green Chemistry" has gained great importance over recent years, being quoted in an increasing number of publications. This fact shows how concern over developing "greener" processes has played a prominent role in the scientific community.
Eduardo F. Sousa-Aguiar   +4 more
doaj   +1 more source

Biochar from Pyrolysis of Biosolids for Nutrient Adsorption and Turfgrass Cultivation [PDF]

open access: yes, 2015
At water resource recovery facilities, nutrient removal is often required and energy recovery is an ever-increasing goal. Pyrolysis may be a sustainable process for handling wastewater biosolids because energy can be recovered in the py-gas and py-oil ...
American Public Health Association (APHA)   +9 more
core   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Electrochemical Umpolung of Bromide: Transition-Metal-Free Bromination of Indole C–H Bond

open access: yesMolecules, 2019
A facile and sustainable electrochemical umpolung of bromide ion protocol was developed under mild reaction conditions. Transition metal catalysts and exogenous chemical oxidants were obviated for the bromination of C⁻H bond. Notably, graphite rod,
Pan Zhang   +7 more
doaj   +1 more source

Illinois River Volunteer Monitoring [PDF]

open access: yes, 2009
Understanding how water quality conditions change along a land use gradient and over time is important for sustainable watershed management. Therefore, a volunteer monitoring program was created to measure water chemistry at 37 established sites within ...
Haggard, B.E., Massey, L.B.
core   +2 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Sustainable synthesis of Pd(II) pincer complexes under conditions of liquid-assisted grinding

open access: yesGreen Chemistry Letters and Reviews
Different mechanochemical tools continue to encompass new fields of synthetic chemistry, often suggesting yield and rate enhancement along with the reduced waste production and simplified product isolation.
Diana V. Aleksanyan   +6 more
doaj   +1 more source

Self-healing composites: A review [PDF]

open access: yes, 2015
Self-healing composites are composite materials capable of automatic recovery when damaged. They are inspired by biological systems such as the human skin which are naturally able to heal themselves.
Ji, Chunqian   +2 more
core   +2 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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