Results 71 to 80 of about 4,447,948 (227)

Toward system innovation for more sustainable chemistry: insights into consumers’ perceptions, knowledge, and behavior related to traceability and product design strategies along leather supply chains

Frontiers in Sustainability
The leather industry is a complex system with multiple actors that faces a fundamental transition toward more sustainable chemistry. To support this process, this article analyzes challenges of the industry and consumers’ roles as a nexus of transition ...
Charis Eisen, Julian Schenten, Anna Theis, Anna Theis, Jonas Rehn-Groenendijk, Marvin Helferich, Marvin Helferich, Helena Müller, Daniel Hanss   +8 more
doaj   +1 more source

Task-Specific Organic Salts and Ionic Liquids Binary Mixtures: A Combination to Obtain 5-Hydroxymethylfurfural From Carbohydrates

Frontiers in Chemistry, 2019
The increase in energy demand and depletion of fossil fuels are among major issues of modern society. Valorization and transformation of raw materials in products of industrial value represent a challenge.
Salvatore Marullo, Carla Rizzo, Francesca D'Anna   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Green Chemistry; Sustainability an Innovative Approach (Green Chemistry and Sustainability)

, 2022
Green chemistry is an approach to the design, manufacture and use of chemical products to intentionally reduce or eliminate chemical hazards. It focuses on the reduction, recycling/ elimination of the use of toxic and hazardous chemicals in production processes by finding creative, alternative routes for making the desired products that minimize the ...
openaire   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Sustainable communities policy review : Stoke [PDF]

, 2012
This report is part of the evidence base for 'In-depth review of sustainable communities policy'.This paper includes evidence collated from an Sustainable Development Commission visit, Audit Commission North Staffordshire Pathfinder report (2004) and ...
Sustainable Development Commission
core   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Public attitudes to sustainable development [PDF]

, 2012
There is a lot of information around on public attitudes to sustainable development, with varying degrees of reliability and relevance. Most of the work referred to here is UK based and comes from DETR, the British Social Attitudes survey and MORI ...
Sustainable Development Commission
core   +2 more sources

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source