Results 81 to 90 of about 487,239 (300)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Needs And Strategies For Curriculum Reform In Chemistry Education For Sustainable Development In Secondary Schools [PDF]
, 2016 Education is the life wire and indispensable variable in any sphere of sustainable development of a nation. Effective chemistry education is an essential integral for both science and technology sustainable development.
BANKOLE, I. S., SANYAOLU, O. P.
core
Green chemistry and the biorefinery concept [PDF]
, 2013 Green Chemistry and Biorefinery concepts are two approaches helping to develop new and more sustainable processes. The implementation of both methodologies impels to fossil-independent future with bioeconomy based on natural feedstock like biowaste and ...
Lukasik, Rafal M., Morais, Ana Rita C.
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Challenges of a feasible route towards sustainability in environmental protection [PDF]
, 2010 Anaerobic processes for treatment of low and high strength wastewaters and solid wastes constitute the core method in the natural biological mineralization (NBM) treatment concept.
Lettinga, G.
core +3 more sources
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Green Processing and Synthesis, 2012 Sustainable chemistry is the attempt to design chemical products and processes that reduce or eliminate the use and generation of hazardous substances, minimize waste and energy consumption, favor renewable resources and integrate aspects of recycling ...
Hempel Maximilian
doaj +1 more source
Metal-Free Reduction of Phosphine Oxides Using Polymethylhydrosiloxane
Inorganics, 2016 A simple protocol is presented here for the use of inexpensive polymethylhydrosiloxane (PMHS), a waste product of the silicon industry, as stoichiometric reducing agent for phosphine oxides to phosphines, a highly desirable reaction to recover P-based ...
Emmanuel Nicolas +6 more
doaj +1 more source
Chemistry: creating new worlds [PDF]
, 2011 The Biennale Kijkduin is an international exhibition at the southerly beach resort of Kijkduin in The Hague. Sea and dunes form the natural setting for the monumental works of glass and light art.
Orta, Jorge, Orta, Lucy
core
STEM materials: a new frontier for an intelligent sustainable world [PDF]
, 2019 Materials are addressed as possible enablers for solutions to many global societal challenges. A foresight exercise has been conducted to identify research paths to design, with a new approach, a generation of materials which can provide multi ...
B Alberts +10 more
core +1 more source