Results 31 to 40 of about 27,023 (260)

Analisis Keunggulan Bersaing Terhadap Kinerja Bisnis Yang Berkelanjutan (Studi Kasus Yayasan Sekolah Daya Utama Kota Bekasi)

Jurnal Akutansi Manajemen Ekonomi Kewirausahaan, 2022
This research is about the Analysis of Competitive Advantage on Sustainable Business Performance. The purpose of this study was to determine the effect of organizational capability and innovation to achieve competitive advantage on sustainable business ...
Doddy Sukma Wirawan
doaj   +1 more source

Analytical Evaluation of Sustainable Competitive Advantage

IFAC Proceedings Volumes, 2013
Abstract This paper introduces a novel idea to model and evaluate the level of sustainable competitive advantage (SCA) in a company's operations, basing on the development directions of the manufacturing strategy and the effectiveness/sufficiency of its supporting resource allocation.
Josu Takala, Yang Liu 0034, Bin Feng, Wenshan Yang   +3 more
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

The Application of Intellectual Capital Approach to Promote a Sustainable Competitive Advantage in the Public Libraries of Khuzestan Province [PDF]

تحقیقات اطلاع‌رسانی و کتابخانه‌های عمومی, 2014
Purpose: This study examines the role of intellectual capital (including human capital, structural capital and relational capital) in creating a sustainable competitive advantage in the public libraries of Khuzestan.
farideh osareh, shiva yazdanfar, afshin ghasemi   +2 more
doaj  

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Study on Resource Allocations for Sustainable Competitive Advantage

Management and Production Engineering Review, 2013
Abstract Today’s concern and problem for most of the companies is the way of surviving and prospering in current and future periods of time in the marketplace. Sustainable competitive ability can be one of the ways of adaptation to the global business and rapid environment requirements.
Takala, Josu, Shylina, Daryna, Forss, Teppo, Malmi, Johannes   +3 more
openaire   +4 more sources