Results 121 to 130 of about 1,998,315 (284)
Social Sustainability: A design research approach to sustainable development [PDF]
, 2011 While issues such as clean production and energy efficiency are still central in sustainable development discourse, attention is increasingly on patterns of consumption at multiple levels in society.
Gregory, Judith +2 more
core +2 more sources
Design for Sustainable Consumption.
Proceedings of DRS, 2004 FutureGround International Conference of the Design Research Society; Melbourne ...
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
INTEGRATION OF SERVICE LIFE IN THE PROCESS OF MANAGEMENT AND DESIGN OF BUILDINGS [PDF]
This article approaches the regulatory framework on the service life of constructed assets and its integration into the management and design process of sustainable buildings.
Silverio HERNÁNDEZ-MORENO
core
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Shanzhai products and sustainable design [PDF]
, 2011 This paper investigates a possible solution to the need for sustainable design through a study of shanzhai products notable for their low price and quality and sometimes, even by their exaggerated design.
Chen, Yi, Clarke, Robert
core
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Molecular Oncology, EarlyView.Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source
, 2013 This is a chapter in a book with the overall description: This is a critical time in design. Concepts and practices of design are changing in response to historical developments in the modes of industrial design production and consumption.
Mazé, Ramia +3 more
core +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Heritage ScienceThis paper collects research information and registered data regarding the relationship between climate change and heritage, aiming to present a comprehensive state of studies and research on the subject.
Marina Panagiota P. Nastou +1 more
doaj +1 more source