Results 101 to 110 of about 16,651,905 (345)
Molecular Oncology, EarlyView.Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva +5 more
wiley +1 more source
Modeling sustainable development [PDF]
Modeling, Identification and Control: A Norwegian Research Bulletin, 1994 Some of the difficulties of extending economic and ecosystem models to allow for long term forecasting applications to the problem of sustainable development are discussed.
openaire +3 more sources
A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer
Molecular Oncology, EarlyView.Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla +15 more
wiley +1 more source
SAGE OpenThis scoping review is intended to examine and consolidate the factors that influence the uptake of COVID-19 vaccines among African university students.
Isaac Nyarko Kwakye +3 more
doaj +1 more source
Ecology and Evolution, 2018 In the animal kingdom, behavioral variation among individuals has often been reported. However, stable among‐individual differences along a behavioral continuum—reflective of personality variation—have only recently become a key target of research. While
Eli S. J. Thoré +5 more
doaj +1 more source
Migration and sustainable development
Proceedings of the National Academy of SciencesTo understand the implications of migration for sustainable development requires a comprehensive consideration of a range of population movements and their feedback across space and time. This Perspective reviews emerging science at the interface of migration studies, demography, and sustainability, focusing on consequences of migration flows for ...
William Neil Adger +3 more
openaire +4 more sources
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Is amblyopia due to inappropriate stimulation of the "sustained" pathway during development? [PDF]
, 1974 Harukuni Ikeda, Michael J. Wright
openalex +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source