Results 11 to 20 of about 2,652,254 (239)
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
Landscape, environment and community impacts of nuclear power [PDF]
, 2012 This paper is the third in a series of 8 that make up the evidence base for SDC report 'The role of nuclear power in a low carbon economy'.This document investigates the landscape impacts of all the processes involved in nuclear power from mining the ...
Sustainable Development Commission
core
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Securing good health for the whole population (Wanless Review) : submission from the SDC [PDF]
, 2012 The Sustainable Development Commission fully supports the terms of reference contained in the document 'Securing good health for the whole population : final report'.
Sustainable Development Commission
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FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
UK Citizen’s Council for the future : creating new spaces for citizens’ voices and long-term thinking in politics [PDF]
, 2012 This paper sets out the rationale and requirement for a citizens' council, a new space for UK citizens to engage with and inform long-term political thinking.Publisher ...
Sustainable Development Commission
core
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Comments back from the Sustainable Communities Summit Workshop : creating communities with low environmental impact [PDF]
, 2012 Based on 'Report back from Sustainable Communities Summit Workshop : creating communities with a low environmental impact'.Publisher ...
Sustainable Development Commission
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Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
FEBS Letters, EarlyView.Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga +6 more
wiley +1 more source
University Hospital Birmingham NHS Foundation Trust [PDF]
, 2012 National Health Service good corporate citizenship assessment model case study.Publisher ...
Sustainable Development Commission
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