Results 41 to 50 of about 552,492 (266)
Co-designing a theory-informed intervention to increase shared decision-making in maternity care
Health Research Policy and Systems, 2023 Background Shared decision-making (SDM) has been shown to improve healthcare outcomes and is a recognized right of patients. Policy requires health services to implement SDM.
Alex Waddell +5 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A high temporal resolution global gridded dataset of human thermal stress metrics
Scientific DataThe human thermal stress indices and datasets are vital for promoting public health and reducing negative environmental impacts as global climate change and extreme meteorological events increase.
Hongdeng Jian +12 more
doaj +1 more source
Growth, Development and Sustainability [PDF]
Revista Română de Statistică, 2013 Describing the relationship of interdependence through the materials balance, will be argued how the economy is a subset of the environment and the environment the natural limit to any economic initiative, or the limits imposed by the laws of thermodynamics.
Irina-Virginia DRAGULANESCU +1 more
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Riverine communities in the Central Amazon are largely subject to erosion and sedimentation risk
Communications Earth & EnvironmentSedimentary processes cause large changes in riverscapes and alter river banks and margins, leading to major hazards for riverine communities. However, regional mapping of the resulting risk remains scarce, especially in remote Amazon regions.
André Zumak +6 more
doaj +1 more source
International Journal of Recycling of Organic Waste in Agriculture, 2018 Purpose In the present study, effect of earthworm-processed MSW was seen on biochemical, physiological, and yield responses of Abelmoschus esculentus L. Methods Plants were grown on different amendment ratios of municipal solid waste vermicompost (MSWVC).
Vaibhav Srivastava +4 more
doaj +1 more source