Results 31 to 40 of about 145,027 (292)
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
International Journal of Digital Earth, 2023 Spaceborne photon-counting LiDAR is significantly affected by noise, and existing denoising algorithms cannot be universally adapted to different surface types and topographies under all observation conditions.
Jieying Lao +6 more
doaj +1 more source
Land, 2023 Land use and land cover (LULC) changes are of vital significance in fields such as environmental impact assessment and natural disaster monitoring. This study, through an analysis of 1432 papers over the past decade employing quantitative, qualitative ...
Caixia Rong, Wenxue Fu
doaj +1 more source
FEBS Letters, EarlyView.Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria +3 more
wiley +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Global annual wetland dataset at 30 m with a fine classification system from 2000 to 2022
Scientific DataWetlands play a key role in maintaining ecological balance and climate regulation. However, due to the complex and variable spectral characteristics of wetlands, there are no publicly available global 30-meter time-series wetland dynamic datasets at ...
Xiao Zhang +5 more
doaj +1 more source
Geology and the Sustainable Development Goals [PDF]
Episodes, 2017 This paper presents an overview and visualisation of the role of geology in the Sustainable Development Goals (SDGs). These internationally-agreed goals aim to eradicate global poverty, end unsustainable consumption patterns, and facilitate sustained and inclusive growth, social development, and environmental protection. Through a matrix visualisation,
openaire +3 more sources
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
FEBS Letters, EarlyView.Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
wiley +1 more source
International Journal of Digital EarthThe Multispectral Imager (MII) onboard the newly launched SDGSAT-1 holds significant promise for monitoring and understanding variations in water quality within nearshore water systems, with an impressive spatial resolution of 10 m, seven spectral bands ...
Shenglei Wang +8 more
doaj +1 more source
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
FEBS Open Bio, EarlyView.Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian +6 more
wiley +1 more source